Nac vs Tudca for liver

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Has anyone tried Tudca instead of NAC for liver health? Due to lots of lifting my liver enzymes are always high end of normal. Only supplements are vitamin d, multi vitamin, magnesium gylcerate, and my trt. Hearing tudca is a little better then nac but nac seems much easier to find.
 
Defy Medical TRT clinic doctor
Thanks for posting this. I’ve had high liver enzymes for years. And I had a liver scan that was fine. And other labs are always fine (GGT?) my docs have always looked at whatever other labs and said seems liver function is fine just the ALT AST will be in 50s-80s. My one doc says it’s likely the lifting but still makes me not feel that good. And some forums guys say quit exercise for two weeks and do labs. Ugh I don’t want to do that. It’s hard enough somedays to get to gym on sheer will. If I stop for two weeks at my age it’s a hassle to get back in groove. I’ve never heard of this supplement though. I’ve been on NAC for years.
 

MarcoFL

Well-Known Member
It was crazy the impact it had with so little I was taking and have had high alt-ast for years! I saw it on a video of a young man on TRT and lifter saying everyone should be on it. All my other results were fine and this helped bring alt and ast in Line too.
 
Wonder why none of my integrative or functional medicine docs have mentioned this ? They’re all pretty wide folks and all about supplements. Ever since I’ve been on TRT I’ve had the issue but if it’s from lifting heavy I maybe always had it, just never did regular blood labs before TRT so I’m always aware of it now. I don’t drink ever. Haven’t in years. Don’t do orals. Just TRT, HGH, HCG, Arimidex and T3/T4. Plus supplements. Have recently added small dose cialis daily , selegaline and Wellbutrin to try to boost libido. And oh I take LDN for pain and Xyrem for sleep. My docs said none of it should raise my liver values. It doesn’t make me feel good to just say it’s heavy lifting because so many other guys lift heavy and their labs don’t show high liver enzymes....
 

apsjiml

Member
When I see elevated liver enzymes the first things I think of is Iron Overload. or Hemochromatosis. Have you had a full iron panel with saturation and ferritin? If it were me, I would get a full iron panel If I have not already
 
When I see elevated liver enzymes the first things I think of is Iron Overload. or Hemochromatosis. Have you had a full iron panel with saturation and ferritin? If it were me, I would get a full iron panel If I have not already

Yes actually my one doctor wants me to be loading up on iron because my ferretin is low. So he has wanted me eating lots of organ meats and taking liver tabs. In the past my iron was Always high for my annual work physical. But then I started donating blood every two months. I just got labs in mail yesterday actually.

Ferritin is 35 low (range 38-380) but I donated blood maybe two weeks before the lab. If that makes a difference as the one doc wanted me to stop donating.

Iron total 136 (range 50-180)
Iron binding capacity 338 (range 250-425)
% saturation 40 (range 20-48)

AST 83 and ALT 77. Usually they’re a little lower but still in high range. But I’m lifting heavy and doing intervals 4-6 days a week. However so are many other guys and they don’t seem to get these kinds of values.
 
I take Choline and NAC and my liver values has gone down by 25%

I am going to speak to my doctors about TUDCA. And now that you mention choline there was an old school supplement bodybuilders took for liver That I think involved choline and 2-3 other ingredients but it’s slipping my mind af moment.
 

apsjiml

Member
Yes actually my one doctor wants me to be loading up on iron because my ferretin is low. So he has wanted me eating lots of organ meats and taking liver tabs. In the past my iron was Always high for my annual work physical. But then I started donating blood every two months. I just got labs in mail yesterday actually.

Ferritin is 35 low (range 38-380) but I donated blood maybe two weeks before the lab. If that makes a difference as the one doc wanted me to stop donating.

Iron total 136 (range 50-180)
Iron binding capacity 338 (range 250-425)
% saturation 40 (range 20-48)

AST 83 and ALT 77. Usually they’re a little lower but still in high range. But I’m lifting heavy and doing intervals 4-6 days a week. However so are many other guys and they don’t seem to get these kinds of values.


Iron -serum - is not really a very good marker for iron status. Hematologist will typically look at ferritin and they don't like to see that much below 50 and they look at % sat which should be 25 to 35% and not above 45%. Then is ast and alt are elevated I would if it were me want a full thyroid panel with free and total t3, free t4, tsh and reverse t3 if I could . Typically the average healthy person has a free t3 in the 3.5 to 3.8 range somewhere in there (range of 2 to 4.2)
 

ERO

Member
Tudca works great for me to lower liver enzyme values. Mine were never super high but always above normal. NAC never seemed to do much "on paper" anyway, but Tudca brought them right down. I take 500 mg daily now.
 

apsjiml

Member
Wonder why none of my integrative or functional medicine docs have mentioned this ? They’re all pretty wide folks and all about supplements. Ever since I’ve been on TRT I’ve had the issue but if it’s from lifting heavy I maybe always had it, just never did regular blood labs before TRT so I’m always aware of it now. I don’t drink ever. Haven’t in years. Don’t do orals. Just TRT, HGH, HCG, Arimidex and T3/T4. Plus supplements. Have recently added small dose cialis daily , selegaline and Wellbutrin to try to boost libido. And oh I take LDN for pain and Xyrem for sleep. My docs said none of it should raise my liver values. It doesn’t make me feel good to just say it’s heavy lifting because so many other guys lift heavy and their labs don’t show high liver enzymes....



Then I would check your thyroid levels with free t3, total t3, and reverse t3, making sure to skip thyroid meds the morning of the lab test. I used to have this, I have a diodinase gene defect and do not convert to t3 well at all and would end up with super high reverse t3.
 
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