my TRT dilemma

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mlc2010

Member
34 Years old guy.. had lifelong erectile dysfunction, I have to use 40mcg of caverject to obtain an erection. Without the erection dies as soon as I stop stimulating

Had doppler test done, normal

tried t3 for a year, no effect

hormones, normal.. except.. I have high levels of SHBG. I read a study that shows high levels of shbg means low free testosterone = ED

My only option is.. testosterone treatment, or.. the implant.. so my question is

No doctor in UK will prescribe TRT for high shbg with high levels of total testosterone, however I have sourced some and going to try it out. We know regular injections of testosterone will lower SHBG. My main question is, is it worth the risk?

Also, I have slow transit constipation and anismus, which means my pelvic floor is out of whack. there is a study here which shows test can strengthen it

Muscles of the trunk and pelvis are responsive to testosterone administration: data from testosterone dose-response study in young healthy men. - PubMed - NCBI
 
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BigBamBoo

Active Member
My SHBG is 75+.....and I am 50. Never had a problem with ED.

TRT is no guarantee of a “cure” to your ED.

Hopefully others will chime in with something helpful.
 

Systemlord

Member
If Free T is low, that puts you in the same category of someone with low testosterone.

You should also consider Balance My Hormones in Dorset.
 

Joey786

Active Member
Steroids are legal in the uk. If doc won’t prescribe use other avenues. Implant should be absolutely last option. Change docs if you have to. With shbg that high you probably need much higher total testosterone. Do you have any other symptoms of low testosterone?
 

mlc2010

Member
Steroids are legal in the uk. If doc won’t prescribe use other avenues. Implant should be absolutely last option. Change docs if you have to. With shbg that high you probably need much higher total testosterone. Do you have any other symptoms of low testosterone?

its easier to get heroin in UK than TRT, doc will not prescribe them for high SHBG, they prob only look at total, and even then you have to be under range, this applies to all NHS doctors

My mental health is fine

I can't grow a beard ( genetics )
I have low muscles mass, but I have always been like that

I don't want TRT to bulk up, I could not care less about muscles. I want to regain some sort of erectile function back

I have been tested for androgen insens syndrome, negative
 

mlc2010

Member
Can you get a DHT prescription? Its legal and will bring down shbg more than regular T.

you mean winstrol or proviron?

winstrol will suppress my natural test, but does lower shbg

I have bloodwork which shows proviron does not lower shbg, tried it on many occasions
 

madman

Super Moderator
Key points

■ Testosterone levels can reflect perturbations in all three dimensions (organic, intrapsychic and relationship) of erectile dysfunction (ED)

■ Testosterone is important not only in controlling the mechanical process of penile erection, but it also controls male sexual behavior and attitudes

■ Testosterone replacement therapy (TrT) should be considered the first-line treatment in hypogonadal patients with ED

■ TrT monotherapy might not be adequate in all cases of ED because of the multifactorial pathophysiology of this disorder

■ In these cases, combination therapy with phosphodiesterase 5 inhibitors might improve outcomes indirectly, several of the mechanisms that lead to erection and detumescence
 

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madman

Super Moderator
CONCLUSIONS

Overall, available data indicate that T represents an important modulator of all the steps involved in the regulation of the male sexual response cycle. This association is attenuated in the epidemiologic studies because, besides hormones, other factors including organic, relational and intrapsychic determinants can modulate androgens’ role. Evidence arising from interventional studies confirms a possible role of TRT in ameliorating several aspects of sexual functioning including libido, erectile function and overall sexual satisfaction. Conversely, data on the role of TRT in improving orgasmic function are more conflicting and analyzed only in a limited number of RCTs. It is important to recognize that, whatever outcome is considered, the effects of TRT are clearly evident only in the presence of hypogonadal status (ie, total T < 12 nmol/L), whereas the positive effects of TRT are no longer confirmed for higher T levels. In addition, TRT alone can be effective in restoring only milder forms of ED, whereas the combined therapy with other drugs is required when more severe vascular damage is present.





*TRT alone can be effective in restoring only milder forms of ED, whereas the combined therapy with other drugs is required when more severe vascular damage is present.
 

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mlc2010

Member
Great post madman. Mlc2010 you need to try trt.

yeah, I was aware it works with hypo patients, but does having high shbg classify me as hypo, I see conflicting reports everywhere that lowering SHBG has no effect

have you ever seen any evidence from this site that high shbg people benefited from TRT?

I have had test in my draws since june, I'm not scared of needles but I'm quite nervous injecting this
 

Joey786

Active Member
Actually from what I’ve read guys with high shbg have more success with trt. The key is taking enough testosterone to increase your free test to where you feel good. I haven’t heard of anyone having success with lowering their shbg in order to increase free test. Injecting isn’t bad at all. Just use a 27g or smaller. I would be more worried about the implant than trt.
 

mlc2010

Member
Actually from what I’ve read guys with high shbg have more success with trt. The key is taking enough testosterone to increase your free test to where you feel good. I haven’t heard of anyone having success with lowering their shbg in order to increase free test. Injecting isn’t bad at all. Just use a 27g or smaller. I would be more worried about the implant than trt.

Yeah its defo worth a try and low risk, I will start soon, I have all the needles in place, 6 years of research but that first injection is always nervy

I was going to try 250mg a week, but that seems a bit high, so might do 150mg, then get bloods after 6 weeks, as I read TEST E takes 3 weeks to kick in?
 

wsj357

Member
yeah, I was aware it works with hypo patients, but does having high shbg classify me as hypo, I see conflicting reports everywhere that lowering SHBG has no effect

have you ever seen any evidence from this site that high shbg people benefited from TRT?

I have had test in my draws since june, I'm not scared of needles but I'm quite nervous injecting this


Stop worrying about high shbg. If you dose and cannot reach an optimal free t level then try a new dose until it’s reached.

All of our hormones must be in balance.

Working on our mind to muscle activation is also important. Talking about the mind. I had to allow my brain to heal because of neuroplasticity. There’s more to ED than hormones. I had low t in the gutter but still had erections hard enough to penetrate and lasted for the entire duration.

Sometimes folks must get honest with themselves and look at their lifestyle and if that has caused long term harm in the sex department.

I had ED for a few years and it was fixed by stopping all sexual activity. I was told “stop touching it”.. stop porn. Stop trying to see if it works today. I let my body heal fully and work up one day with the most insane appetite for sex. They gave me trt before this fix and that did nothing for me.

Not saying this is your answer, but it could be a good example of how TRT is not the only solution.
 

mlc2010

Member
Stop worrying about high shbg. If you dose and cannot reach an optimal free t level then try a new dose until it’s reached.

All of our hormones must be in balance.

Working on our mind to muscle activation is also important. Talking about the mind. I had to allow my brain to heal because of neuroplasticity. There’s more to ED than hormones. I had low t in the gutter but still had erections hard enough to penetrate and lasted for the entire duration.

Sometimes folks must get honest with themselves and look at their lifestyle and if that has caused long term harm in the sex department.

I had ED for a few years and it was fixed by stopping all sexual activity. I was told “stop touching it”.. stop porn. Stop trying to see if it works today. I let my body heal fully and work up one day with the most insane appetite for sex. They gave me trt before this fix and that did nothing for me.

Not saying this is your answer, but it could be a good example of how TRT is not the only solution.

Thanks for reply dude, but I have done the abstain from porn and orgasm, even went aslong as 6-8 months without any orgasm. i'm only young once, I'm letting life go by

Been trying this and that for ages, my plan is to try trt.. if it doesn't work, stop

and then the penile implant
 
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