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Peptide Forums (GHRH, Sermorelin, etc)
General Peptide Use & Information
MK-677 and my IGF-1 Levels
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<blockquote data-quote="BigTex" data-source="post: 225911" data-attributes="member: 43589"><p>In a 12 month study conducted on postmenopausal osteoporotic women, 25 mg of MK-677 per day administered with or without alendronate for 12 months increased IGF-1 levels by approximately 40%. So doing the math, if you had a baseline of 56ng/ml and got a 75 ng/ml after using MK-677, they you pretty much got what research has show to be possible. 40% of 56 is 78. Had you done 25mg of MK-677 you might have been at or slightly above 40%.</p><p></p><p></p><p>Murphy MG, Weiss S, McClung M, Schnitzer T, Cerchio K, Connor J, Krupa D, Gertz BJ; MK-677/Alendronate Study Group. Effect of alendronate and MK-677 (a growth hormone secretagogue), individually and in combination, on markers of bone turnover and bone mineral density in postmenopausal osteoporotic women. J Clin Endocrinol Metab. 2001 Mar;86(3):1116-25. doi: 10.1210/jcem.86.3.7294. PMID: 11238495.</p><p></p><p>[URL unfurl="true"]https://pubmed.ncbi.nlm.nih.gov/11238495/[/URL]</p><p></p><p>If you are looking for more IGF-1 you might try adding a GHRP and GHRH with it. Or even better, lower dose hGH.</p></blockquote><p></p>
[QUOTE="BigTex, post: 225911, member: 43589"] In a 12 month study conducted on postmenopausal osteoporotic women, 25 mg of MK-677 per day administered with or without alendronate for 12 months increased IGF-1 levels by approximately 40%. So doing the math, if you had a baseline of 56ng/ml and got a 75 ng/ml after using MK-677, they you pretty much got what research has show to be possible. 40% of 56 is 78. Had you done 25mg of MK-677 you might have been at or slightly above 40%. Murphy MG, Weiss S, McClung M, Schnitzer T, Cerchio K, Connor J, Krupa D, Gertz BJ; MK-677/Alendronate Study Group. Effect of alendronate and MK-677 (a growth hormone secretagogue), individually and in combination, on markers of bone turnover and bone mineral density in postmenopausal osteoporotic women. J Clin Endocrinol Metab. 2001 Mar;86(3):1116-25. doi: 10.1210/jcem.86.3.7294. PMID: 11238495. [URL unfurl="true"]https://pubmed.ncbi.nlm.nih.gov/11238495/[/URL] If you are looking for more IGF-1 you might try adding a GHRP and GHRH with it. Or even better, lower dose hGH. [/QUOTE]
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Peptide Forums (GHRH, Sermorelin, etc)
General Peptide Use & Information
MK-677 and my IGF-1 Levels
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