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Testosterone Replacement, Low T, HCG, & Beyond
When Testosterone Is Not Enough
Mineralized Peyronie’s plaque has a phenotypic resemblance to bone
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<blockquote data-quote="madman" data-source="post: 212655" data-attributes="member: 13851"><p><strong>Figure 7. <u>Histology</u>: Osteocytic lacuna-like regions were localized within a higher mineralized collagenous and DMP-1-positive matrix that also is lower in Zn counts. However, this region is surrounded by a softer matrix with higher Zn counts. The presence of blood vessels within these regions was also observed. (A) The 2D virtual section illustrates regions with higher mineral density. (B) H&E illustrates the distribution of cells relative to the matrix. The presence of innervation was detected (black arrow). (C) Gomori trichrome staining illustrates a collagenous matrix in both harder (outlined) and softer regions. (D) Alcian Blue staining reveals the absence of negatively charged proteoglycans in the higher mineralized regions (outlined). (E) Safranin-O counterstained with fast green illustrates the plausible presence of cartilaginous tissues within the higher mineralized regions (outlined). Fast green-positive areas are observed surrounding blood vessels within the outlined regions. The presence of innervation was detected (black arrow). (F) DMP-1 was immunolocalized in higher mineral density regions (outlined). The presence of innervation was detected (black arrow).</strong></p><p><strong>[ATTACH=full]17935[/ATTACH]</strong></p><p><strong>[ATTACH=full]17936[/ATTACH]</strong></p></blockquote><p></p>
[QUOTE="madman, post: 212655, member: 13851"] [B]Figure 7. [U]Histology[/U]: Osteocytic lacuna-like regions were localized within a higher mineralized collagenous and DMP-1-positive matrix that also is lower in Zn counts. However, this region is surrounded by a softer matrix with higher Zn counts. The presence of blood vessels within these regions was also observed. (A) The 2D virtual section illustrates regions with higher mineral density. (B) H&E illustrates the distribution of cells relative to the matrix. The presence of innervation was detected (black arrow). (C) Gomori trichrome staining illustrates a collagenous matrix in both harder (outlined) and softer regions. (D) Alcian Blue staining reveals the absence of negatively charged proteoglycans in the higher mineralized regions (outlined). (E) Safranin-O counterstained with fast green illustrates the plausible presence of cartilaginous tissues within the higher mineralized regions (outlined). Fast green-positive areas are observed surrounding blood vessels within the outlined regions. The presence of innervation was detected (black arrow). (F) DMP-1 was immunolocalized in higher mineral density regions (outlined). The presence of innervation was detected (black arrow). [ATTACH type="full"]17935[/ATTACH] [ATTACH type="full"]17936[/ATTACH][/B] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
When Testosterone Is Not Enough
Mineralized Peyronie’s plaque has a phenotypic resemblance to bone
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