Low penile sensitivity issue - neurotransmitter related?

[EdinSFO]

I've struggled with low sensitivity my whole life, with it just getting worse as I get older. I'm 53 and I've been on TRT now for about eight years. There are some magic times when it seems like everything is normal, but those are few and far between. I have tried various things (HCG, raising/lowering estrogen, Wellbutrin, etc) with nothing helping at all. Recently, I had a bad sinus infection for which I used Sudaphed (pseudoephedrine). One night I forgot I'd just taken two and took two more for a total of 120mg. After a couple hours I noticed that my penis was extremely sensitive and I was able to orgasm very quickly. So, my question is... what exactly caused this to happen? It sounds like it's neurotransmitter related, and I'd like to see someone, but what kind of doctor? I've read that an andrologist would be better than a urologist. Anyone else have any input? Sudafed acts as a vasoconstrictor as well as messes with norepinephrine. It would be great to take something that worked without creating erection issues.

 

[slicktop]

Man, I don't know what to tell you scientifically, but I'll tell ya this: I don't have sensitivity issues at all, but when I do take sudafed for a sinus issue (which is rare) I almost can't wait to get my wife alone because the sex is NEXT LEVEL with sudafed in my system. Orgasms on par with or surpassing what I experienced on ecstasy in my late 20's.

 

[Systemlord]

You should update you thread title, you would get more traffic.

 

[Nelson Vergel]

In my opinion, it is blood flow related. Better blood flow even in the flacid state increases the temperature of the penile glans and its sensitivity. TRT, HCG, ED drugs and increased nitric oxide can improve penile blood flow.

How to improve penis sensitivity

 

[Vince]

So you’ve got a cold and you’ve been taking some over-the-counter drugs to get over it. You’re in the mood because your temperature is finally down, but so is your guy. Why? Paul R. Gittens, MD says your cold medicine is to blame: “Sudafed, or any cold medication that has the active ingredient Pseudoephedrine leads to constriction of the penile vessels and erectile dysfunction,” he notes.

Common Medications That Affect Sexual Performance

 

[EdinSFO]

My problem is NOT erectile dysfuntion. Please re-read my post. It is with low sensitivity in my penis.... which for a brief window, was alleviated with sudafed. I'm pretty sure I have some sort of chemical signaling issue with the nerves. I have had a rock hard penis with great blood flow but almost no sensitivity.

 

[mrjg]

My problem is NOT erectile dysfuntion. Please re-read my post. It is with low sensitivity in my penis.... which for a brief window, was alleviated with sudafed. I'm pretty sure I have some sort of chemical signaling issue with the nerves. I have had a rock hard penis with great blood flow but almost no sensitivity.

Which version of Sudafed are you taking and what is the main active ingredient?

 

[EdinSFO]

Which version of Sudafed are you taking and what is the main active ingredient?

The real version, with Pseudoephedrine. I've read that it increases norepinephrine in the body.

 

[mrjg]

The real version, with Pseudoephedrine. I've read that it increases norepinephrine in the body.

Ok, my personal experience with pseudoephedrine is that it causes me erectile dysfunction when I take it, but that's just a regularly dose amount. I understand you're posting about "increased penile sensitivity" and not erectile dysfunction, but I just thought I'd mention my experience. If I can find my Sudafed I'll try a 120mg dose to see what happens. A 120mg dose of Sudafed is what's suggested when you have priapism, so that's why erectile dysfunction come up so much with searches online involving Sudafed and penile issue. If I find anything involving penile sensitivity I'll post it here.

 

[SilverSurfer]

The real version, with Pseudoephedrine. I've read that it increases norepinephrine in the body.

Pseudoephedrine is an adrenergic amines drug....aka a stimulant. Stimulates are notorious for making men horny, but on the flip side also makes it harder to climax...hence the term “crystal dick”. The vasoconstriction action of those types of drugs puts pressure on the prostate which your brain translates into a pleasurable feeling.

 

[meelord]

It is the speed, dopamine connection. If you really want to test take an Adderall. Not advocating irresponsible behavior but you will get your answer.

 

[Vvs1]

Yeah, I think that it’s neurological.

If you get a pump ie more blood flow, in the gym, it doesn’t make your muscles more sensitive.