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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
How can one increase SHBG when it is too low?
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<blockquote data-quote="AbsoluteZ3R0" data-source="post: 75339" data-attributes="member: 15174"><p>As far as I know, all SERMs raise SHBG. I believe this is due to the E2-agonizing qualities they exhibit on specific receptors. Of course, the issue with SERMs is that the varying interactions they exhibit on E2 receptors can often make their effects unpredictable. I would imagine that using any of them effectively in conjunction with a standard TRT protocol would be disastrously convoluted. The most commonly used one is tamoxifen, but only temporarily to combat gynecomastia. I can't imagine staying on a SERM throughout the entirety of a trt regimen, and I would imagine that SHBG would return to baseline after discontinuation. Incidentally, I used clomid for a few months and my SHBG didn't budge (it was actually a few decimals lower on clomid than it was pre-clomid, not a significant difference).</p></blockquote><p></p>
[QUOTE="AbsoluteZ3R0, post: 75339, member: 15174"] As far as I know, all SERMs raise SHBG. I believe this is due to the E2-agonizing qualities they exhibit on specific receptors. Of course, the issue with SERMs is that the varying interactions they exhibit on E2 receptors can often make their effects unpredictable. I would imagine that using any of them effectively in conjunction with a standard TRT protocol would be disastrously convoluted. The most commonly used one is tamoxifen, but only temporarily to combat gynecomastia. I can't imagine staying on a SERM throughout the entirety of a trt regimen, and I would imagine that SHBG would return to baseline after discontinuation. Incidentally, I used clomid for a few months and my SHBG didn't budge (it was actually a few decimals lower on clomid than it was pre-clomid, not a significant difference). [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
How can one increase SHBG when it is too low?
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