High levels of two hormones in the blood raise prostate cancer risk

[captain]

Increase up to .75 when starting TRT. If more you need to look into it. You may need to retest to confirm it is accurate.

 

[TorontoTRT]

Yeah the rise from 0.77 to 1.8 really freaked me out. They're right, sometimes it's best to not even check PSA until after 50.

 

[TorontoTRT]

You're saying guys starting trt see a rise of about 0.75 ?

 

[captain]

Dr. Crisler TRT guide stated if a rise over .75 you need to stop TRT.

 

[TorontoTRT]

Have guys on here notice fluctuations in their PSA?

 

[DragonBits]

So is a PSA of 1.8 ok for a 43 yo?

What I was 43 my PSA was 2.1.

23 years later at 65 it was 2.4. Not much change at all considering I had also been on TRT for 5 of those 23 years.

(Lately, the last 18 months, PSA has jumped around quite a bit, up to 4.2, down to 3.4, back up to 4.8 and then back down to 3.8.)

 

[TorontoTRT]

So mine jumping around from 0.93 to 0.77 to 1.8 is not a big deal per se? (In 20 months)

 

[captain]

A PSA velocity greater than 0.75 ng/mL/y, regardless of the baseline PSA, or a nodule on digital rectal examination while on TRT should prompt further investigation with a prostate biopsy.
Rising PSA during Testosterone Replacement Therapy

 

[TorontoTRT]

Based on this calculator my PSA velocity is
0.44 ng/ml/yr
April 2018 - 0.93 PSA
January 2019 - 0.77 PSA total PSA free % 45
November 2019 - 1.8 PSA
(Will repeat test in 6 weeks)

USRF - PSA Velocity

 

[M.J]

Could it be just inflammation or something? 2 years ago it was 0.93 then I started trt. 3 months into TRT it dropped to 0.77 with a free PSA % total of 35% and 45% which is good. But now randomly 10 months after that it's 1.8. it does feel slightly irritated due to constipation and huge bowel movements and straining which I think irritates the prostate as it's right there.

I used to be around 1.4 after trt went to 1.69, then back down to 1.46 after three month. I stopped trt after that and it went down again to 1.4.
Doing clomid now to see if it can help otherwise trying different protocol trt after this.