Help - 4 weeks on TRT + Nipple Pain / Estradiol = 20 pg/ml ???

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Drug350

Member
So I just got my 5th weekly shot, 100 MG's Testosterone Cypionate. My nipples starting hurting about the 3rd week, and continue to hurt. I bumped into a wall the other day hitting my chest /nipple and it fu_kin hurt like hell !!!! If I touch my nipples, pushing up and down, they hurt or push directly on them they hurt bad. They also look bigger (nipples). I had 3 blood tests done prior to starting TRT, and my numbers looked like this:

Testosterone = 169 NGDL
Free Testosterone = 3.1 NGDL
Bioavailable Testosterone = 72.6 NGDL
SHBG =34 nmol/L
TSH = 2.64 uiU/ml
Prolactin = 14.6 ng/ml
Estradiol = 21 pg/ml
LH = 3 mlU/ml
FSH = 4 mlU/ml
PSA = .5 ng/ml

I just had blood work ran today and I expected my Estradiol to be significantly higher, but it wasn't. It even dropped from 21 pg/ml before, to 20 pg/ml now. I don't believe she ordered a Prolactin test again, although I'm thinking that could very well be the reason my nipples are hurting. I do have some gyno from past cycles I've done when I was younger and I'm looking into gyno surgery so I can have these glands removed and never have to worry about these problems again. In the meantime, would it be worth taking a small dose of anastrozole or tiny dose of letro to see if there's any changes ??? Honestly, my estrogen at 20 I though was almost perfect, perhaps even on the lower side for being on TRT. I wouldn't think I'd want it much lower than 20 pg/ml. Thank you in advance for any and all suggestions.
 
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Systemlord

Member
I just had blood work ran today and I expected my Estradiol to be significantly higher
A lot of guys think estrogen is the boogie man, that it solely causes nipple pain and tenderness. I have nipple pain, burning in the weeks leading up to a steady state and these issues went away after 6 weeks.

Your hormone levels are in flux, this is what’s causing these symptoms and the nipple pain may very well disappear after 6 weeks.
 

Drug350

Member
A lot of guys think estrogen is the boogie man, that it solely causes nipple pain and tenderness. I have nipple pain, burning in the weeks leading up to a steady state and these issues went away after 6 weeks.

Your hormone levels are in flux, this is what’s causing these symptoms and the nipple pain may very well disappear after 6 weeks.
OK. Awesome. Thank you. I just got my testosterone numbers back. I shoot 1/2 CC, so 100 MG's on Tuesday. I had my bloods drawn a week later, Tuesday night, so these were my numbers a week from last shot, a month in. My testosterone numbers have really shot up. I realize the ranges below are probably much lower than most TRT Clinics, but this is through my Urologist and it's what they go by. These numbers are telling me that I must be above 1000, maybe quite a bit, the first few days after my shot. I was actually surprised to see these numbers this high a full week later. I'm thinking my estrogen could be much higher the first few days, than slowly dropping to 20 pgml a week later. I'm going to split the dose, and go every 3 days instead of 1 large dose once a week and see if the nipple pain goes away.

Total = 610 NGDL (normal range 200 - 745)
Free = 11.8 NGDL (normal range 3.1 - 12.8)
Bioavailable = 276.5 NGDL (normal range 71.7 - 300)
SHBG = 40.00 nmol (normal range 13 - 74 nmol)
 

Drug350

Member
What other medications are you taking? Any growth hormone or peptides?

Nipple pain has been discussed several times.
No. Absolutely NOTHING. I haven't done any gear in 2+ years. No peptides whatsoever. The only drugs I'm on are TRT and daily Cialis. I'd love to find an online clinic that would supply GH, like 1 - 2 IU's daily, weekend's off, would be great. Absolutely zero chance my GP or Urologist would write GH.
 
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