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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
HCG Mixing Needle, Sterility, discard after 1 month?
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<blockquote data-quote="Re-Ride" data-source="post: 36404" data-attributes="member: 8395"><p>A lyophilized powder can be packaged in an inert gas OR a vacuum. In the latter there is neither pressure nor vacuum in the vial. To reconstitute the powder the packaged gas must escape during addition of the bac water. If the technician fails to allow for this he will pressurize the vial. This results in:</p><p>a) reconstitute spaying out past the needle </p><p>b) pressure which might damage delicate compounds</p><p></p><p>Many techs will withdraw the inert gas to create a slight vacuum before reconstitution. The following method saves this step and reduces puncture damage to the vial stopper:</p><p></p><p>Seat vial on sturdy flat surface. Wipe stopper with alcohol and let dry. A 21G stubby and 10 ml syringe allows gas in the vial to slowly bubble up through the bac water filled syringe as it is displaced by water accumulating in the vial. Other gauges work too. A long 30 G obviously will not work well. </p><p></p><p>Left alone the water will gently drip on the hCG. Slight movement of the plunger might assist the process. If the flow stops pull back on the plunger to remove gas from the vial which will bubble up through the bac water in the syringe. Repeat but <em>at no time pressurize the vial by forcing the plunger and bac water in to the vial</em>. </p><p></p><p>This prevents pressure from building inside the vial as water displaces gas. When done pull back to remove as much gas as possible which remains in the vial over the reconstitute before withdrawing the 10 ml syringe. </p><p>---</p><p>Where hCG is packaged in a slight vacuum instead of an inert gas such as Novarel ( I believe), I have found the following:</p><p></p><p>I use the same method as above except at first the flow is greater than might be ideal. Tilt the needle and let the flow hit the wall of the vial. This initial vacuum will dissipate before 10 ml of water can enter the vial. At this point the situation will be as above. There will be some gas in the vial that needs to escape so more water can enter without a resultant pressure building in the vial. That will happen on it's own or you may press the plunger down to inject a ml or two of water then pull back and watch the gas bubble back up through the syringe. </p><p></p><p>The point of this simple technique is that at no time are you pressurizing the vial by forcing water in to it. the last step removes gas and leaves your reconstitute under slight vacuum. </p><p></p><p> Next you will be withdrawing your dose with the smaller injection syringe. Each time you prepare to dose inject the same amount of air in ml volume in to the alcohol swabbed vial as you intend to withdraw. At no time will you ever pressurize your vial or have difficulty withdrawing an aliqot. </p><p></p><p>The short stubby 21G to 25G needles can safely be reused for reconstitution if necessary IF stored in a vial with a little alcohol. Nothing has been in contact with them but bac water assuming good technique. Just make sure they are air dried before use. Mounting them to the 10 ml with the plunger already withdrawn effectively forces any alcohol out and drys the needle. In health care it has become the practice never to reuse a syringe or needle even for reconstitution. Not to debate the wisdom of this but good technique makes it unnecessary. Nice to know should you ever find yourself short of supplies.</p></blockquote><p></p>
[QUOTE="Re-Ride, post: 36404, member: 8395"] A lyophilized powder can be packaged in an inert gas OR a vacuum. In the latter there is neither pressure nor vacuum in the vial. To reconstitute the powder the packaged gas must escape during addition of the bac water. If the technician fails to allow for this he will pressurize the vial. This results in: a) reconstitute spaying out past the needle b) pressure which might damage delicate compounds Many techs will withdraw the inert gas to create a slight vacuum before reconstitution. The following method saves this step and reduces puncture damage to the vial stopper: Seat vial on sturdy flat surface. Wipe stopper with alcohol and let dry. A 21G stubby and 10 ml syringe allows gas in the vial to slowly bubble up through the bac water filled syringe as it is displaced by water accumulating in the vial. Other gauges work too. A long 30 G obviously will not work well. Left alone the water will gently drip on the hCG. Slight movement of the plunger might assist the process. If the flow stops pull back on the plunger to remove gas from the vial which will bubble up through the bac water in the syringe. Repeat but [I]at no time pressurize the vial by forcing the plunger and bac water in to the vial[/I]. This prevents pressure from building inside the vial as water displaces gas. When done pull back to remove as much gas as possible which remains in the vial over the reconstitute before withdrawing the 10 ml syringe. --- Where hCG is packaged in a slight vacuum instead of an inert gas such as Novarel ( I believe), I have found the following: I use the same method as above except at first the flow is greater than might be ideal. Tilt the needle and let the flow hit the wall of the vial. This initial vacuum will dissipate before 10 ml of water can enter the vial. At this point the situation will be as above. There will be some gas in the vial that needs to escape so more water can enter without a resultant pressure building in the vial. That will happen on it's own or you may press the plunger down to inject a ml or two of water then pull back and watch the gas bubble back up through the syringe. The point of this simple technique is that at no time are you pressurizing the vial by forcing water in to it. the last step removes gas and leaves your reconstitute under slight vacuum. Next you will be withdrawing your dose with the smaller injection syringe. Each time you prepare to dose inject the same amount of air in ml volume in to the alcohol swabbed vial as you intend to withdraw. At no time will you ever pressurize your vial or have difficulty withdrawing an aliqot. The short stubby 21G to 25G needles can safely be reused for reconstitution if necessary IF stored in a vial with a little alcohol. Nothing has been in contact with them but bac water assuming good technique. Just make sure they are air dried before use. Mounting them to the 10 ml with the plunger already withdrawn effectively forces any alcohol out and drys the needle. In health care it has become the practice never to reuse a syringe or needle even for reconstitution. Not to debate the wisdom of this but good technique makes it unnecessary. Nice to know should you ever find yourself short of supplies. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
HCG Mixing Needle, Sterility, discard after 1 month?
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