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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
FT using TruT vs Dialysis methods
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<blockquote data-quote="madman" data-source="post: 163519" data-attributes="member: 13851"><p>Not only does it seem odd that with a TT 837 ng/dL and an SHBG on the higher end 52 nmol/L that your FT is only 8.4 ng/dL (reference range 5.2-28.0 ng/dL) which is closer to the bottom end.....it would be hard to believe that anyone at such FT level would feel well let alone pretty good.....and you stated that....<strong>."Still this FT testings and results are confusing and I agree it matters more how you feel then the lab result numbers. <span style="color: rgb(44, 130, 201)">I think I can raise my TT and FT and feel a little better.</span> <span style="color: rgb(184, 49, 47)">But I do feel pretty good now</span>"</strong></p><p></p><p>Now if we want to try and compare as you have done......again keeping in mind that the main issue is the reference ranges between testing methods from the various labs for FT by Equilibrium Dialysis or Ultrafiltration are different and not on the same scale as TruT.....<span style="color: rgb(184, 49, 47)">so until reference ranges are <strong>standardized and there are harmonized reference ranges for Free Testosterone</strong> as have been previously done for Total Testosterone (CDC and its Hormone Assay Standardization program) than doubtful you could do an accurate comparison. </span></p><p></p><p>Here is some of the labs posted by members that had FT tested using ED or Ultrafiltration:</p><p></p><p>Below is the members lab results testing his FT at <span style="color: rgb(184, 49, 47)">Labcorp using.....Testosterone, F EQLIB + T LC/MS (Final).</span></p><p></p><p>As you can see his TT is 1004 ng/dL, SHBG 60.1 nmol/L (high) and Albumin 4.6 g/dL and his FT 18.47 ng/dL (reference range 5.00-21.00 ng/dL).....so even with a high SHBG of 60.1 nmol/L his FT is close to the top end of the reference range.</p><p></p><p>Your TT 837 ng/dL which is not an extreme difference compared to his TT 1004 ng/dL, your SHBG 52 nmol/L is a little lower than his 60.1 nmol/L, and your Albumin 4.2 g/dL is slightly lower than his 4.6 nmol/L.....your FT is 8.4 ng/dL (close to the bottom end of the reference range) and his FT is 18.47 ng/dL (close to the top end of the reference range).</p><p></p><p>Seems odd to have such a significant difference in FT levels when not only is his TT not significantly higher than yours but his SHBG is higher and Albumin is only slightly higher.</p><p>[ATTACH=full]8643[/ATTACH]</p><p></p><p></p><p></p><p></p><p>Now if we take those numbers and use the TruT calculated method.....albeit the reference ranges are on a different scale.</p><p>.</p><p></p><p>TT 1004ng/dL, SHBG 60.1 nmol/L, Albumin 4.6 ng/dL than his FT is 30.73 ng/dL (reference range 16-31 ng/dL).....so his FT is right at the top end of the reference range.</p><p>[ATTACH=full]8639[/ATTACH]</p><p>Now again as you can see when he tested FT using Equilibrium Dialysis his FT 18.47 ng/dL (reference range 5.00-21.00 ng/dL).....is close to the top end of the reference range.</p><p></p><p></p><p></p><p></p><p>Here is another members lab results testing his FT <span style="color: rgb(184, 49, 47)">at Quest Labs using.....Testosterone, FR (DIALYSIS) AND TOTAL (LC/MS/MS).</span></p><p></p><p>The Quest Labs reference range for FT and the units are 35.0-155.0 pg/mL.....different from the previous members Labcorp reference range/units 5.00-21.00 ng/dL.</p><p></p><p>As you can see his TT is very high 1627 ng/dL, SHBG 47 nmol/L and Albumin 4.8 g/dL and his FT is very high 303.3 pg/mL (reference range 35.0-155.0 pg/mL).....so even with a highish SHBG of 47 nmol/L his FT is almost double the top end of the reference range.</p><p>[ATTACH=full]8641[/ATTACH]</p><p>[ATTACH=full]8640[/ATTACH]</p><p></p><p></p><p></p><p>Now if we take those numbers and use the TruT calculated method.....albeit the reference ranges are on a different scale.</p><p></p><p></p><p>TT 1627 ng/dL, SHBG 47 nmol/L, Albumin 4.8 ng/dL than his FT is 52.75 ng/dL (reference range 16-31 ng/dL).....so his FT is over more than 3/4 the top end of the reference range.</p><p></p><p>TruT reference range is <span style="color: rgb(184, 49, 47)">16.4-31.6 ng/dL or 164-316 pg/mL</span>.....so if we take his FT 52.75 ng/dL and covert to pg/mL it would be roughly 528 pg/mL.....so his FT is over 3/4 the top end of the reference range.</p><p>[ATTACH=full]8642[/ATTACH]Now again as you can see when he tested FT using Equilibrium Dialysis his FT is 303.3 pg/mL (reference range 35.0-155.0 pg/mL).....is almost double the top end of the reference range.</p><p></p><p></p><p></p><p>Another members results tested using Equilibrium Dialysis, Vermuelen and TruT calculated.....unfortunately he did not post up labs.....which is needed!</p><p>[ATTACH=full]8645[/ATTACH]</p><p></p><p></p><p>Below is another members lab results testing his FT at <span style="color: rgb(184, 49, 47)">Labcorp using.....Testosterone, F EQLIB + T LC/MS (Final).</span></p><p></p><p></p><p></p><p>He has posted numerous labs stating he normally has high SHBG in the 60-70 nmol/L range.</p><p></p><p>These are his labs from 4/2019.</p><p></p><p>As you can see his TT is 972 ng/dL, SHBG was not tested? but from other labs posted he usually runs high 60-70 nmol/L and Albumin 4.3 g/dL (mean) and his FT 30.62 ng/dL (reference range 5.00-21.00 ng/dL).....so even with a high SHBG 60-70 nmol/L his FT is over 3/4 the top end of the reference range.</p><p>[ATTACH=full]8648[/ATTACH]</p><p></p><p></p><p></p><p></p><p>Now if we take those numbers and use the TruT calculated method.....albeit the reference ranges are on a different scale.</p><p></p><p>Mind you we do not have know his SHBG but will use the higher end number of 70 nmol/L as he usually has SHBG in the 60-70 nmol/L range.</p><p></p><p>TT 972 ng/dL, SHBG 70 nmol/L, Albumin 4.3 ng/dL (mean) than his FT is 30.25 ng/dL (reference range 16-31 ng/dL).....so even with a high SHBG of 70 nmol/L his FT is almost top end of the reference range.</p><p>[ATTACH=full]8647[/ATTACH]</p><p>Now again as you can see when he tested FT using Equilibrium Dialysis his FT 30.62 ng/dL (reference range 5.00-21.00 ng/dL).....is over 3/4 the top end of the reference range.</p><p></p><p>Again we have no idea what his SHBG level was when he had lab work done but he is very well know to have high SHBG as he has stated many times let alone show in lab work he has posted previously.</p></blockquote><p></p>
[QUOTE="madman, post: 163519, member: 13851"] Not only does it seem odd that with a TT 837 ng/dL and an SHBG on the higher end 52 nmol/L that your FT is only 8.4 ng/dL (reference range 5.2-28.0 ng/dL) which is closer to the bottom end.....it would be hard to believe that anyone at such FT level would feel well let alone pretty good.....and you stated that....[B]."Still this FT testings and results are confusing and I agree it matters more how you feel then the lab result numbers. [COLOR=rgb(44, 130, 201)]I think I can raise my TT and FT and feel a little better.[/COLOR] [COLOR=rgb(184, 49, 47)]But I do feel pretty good now[/COLOR]"[/B] Now if we want to try and compare as you have done......again keeping in mind that the main issue is the reference ranges between testing methods from the various labs for FT by Equilibrium Dialysis or Ultrafiltration are different and not on the same scale as TruT.....[COLOR=rgb(184, 49, 47)]so until reference ranges are [B]standardized and there are harmonized reference ranges for Free Testosterone[/B] as have been previously done for Total Testosterone (CDC and its Hormone Assay Standardization program) than doubtful you could do an accurate comparison. [/COLOR] Here is some of the labs posted by members that had FT tested using ED or Ultrafiltration: Below is the members lab results testing his FT at [COLOR=rgb(184, 49, 47)]Labcorp using.....Testosterone, F EQLIB + T LC/MS (Final).[/COLOR] As you can see his TT is 1004 ng/dL, SHBG 60.1 nmol/L (high) and Albumin 4.6 g/dL and his FT 18.47 ng/dL (reference range 5.00-21.00 ng/dL).....so even with a high SHBG of 60.1 nmol/L his FT is close to the top end of the reference range. Your TT 837 ng/dL which is not an extreme difference compared to his TT 1004 ng/dL, your SHBG 52 nmol/L is a little lower than his 60.1 nmol/L, and your Albumin 4.2 g/dL is slightly lower than his 4.6 nmol/L.....your FT is 8.4 ng/dL (close to the bottom end of the reference range) and his FT is 18.47 ng/dL (close to the top end of the reference range). Seems odd to have such a significant difference in FT levels when not only is his TT not significantly higher than yours but his SHBG is higher and Albumin is only slightly higher. [ATTACH=full]8643[/ATTACH] Now if we take those numbers and use the TruT calculated method.....albeit the reference ranges are on a different scale. . TT 1004ng/dL, SHBG 60.1 nmol/L, Albumin 4.6 ng/dL than his FT is 30.73 ng/dL (reference range 16-31 ng/dL).....so his FT is right at the top end of the reference range. [ATTACH=full]8639[/ATTACH] Now again as you can see when he tested FT using Equilibrium Dialysis his FT 18.47 ng/dL (reference range 5.00-21.00 ng/dL).....is close to the top end of the reference range. Here is another members lab results testing his FT [COLOR=rgb(184, 49, 47)]at Quest Labs using.....Testosterone, FR (DIALYSIS) AND TOTAL (LC/MS/MS).[/COLOR] The Quest Labs reference range for FT and the units are 35.0-155.0 pg/mL.....different from the previous members Labcorp reference range/units 5.00-21.00 ng/dL. As you can see his TT is very high 1627 ng/dL, SHBG 47 nmol/L and Albumin 4.8 g/dL and his FT is very high 303.3 pg/mL (reference range 35.0-155.0 pg/mL).....so even with a highish SHBG of 47 nmol/L his FT is almost double the top end of the reference range. [ATTACH=full]8641[/ATTACH] [ATTACH=full]8640[/ATTACH] Now if we take those numbers and use the TruT calculated method.....albeit the reference ranges are on a different scale. TT 1627 ng/dL, SHBG 47 nmol/L, Albumin 4.8 ng/dL than his FT is 52.75 ng/dL (reference range 16-31 ng/dL).....so his FT is over more than 3/4 the top end of the reference range. TruT reference range is [COLOR=rgb(184, 49, 47)]16.4-31.6 ng/dL or 164-316 pg/mL[/COLOR].....so if we take his FT 52.75 ng/dL and covert to pg/mL it would be roughly 528 pg/mL.....so his FT is over 3/4 the top end of the reference range. [ATTACH=full]8642[/ATTACH]Now again as you can see when he tested FT using Equilibrium Dialysis his FT is 303.3 pg/mL (reference range 35.0-155.0 pg/mL).....is almost double the top end of the reference range. Another members results tested using Equilibrium Dialysis, Vermuelen and TruT calculated.....unfortunately he did not post up labs.....which is needed! [ATTACH=full]8645[/ATTACH] Below is another members lab results testing his FT at [COLOR=rgb(184, 49, 47)]Labcorp using.....Testosterone, F EQLIB + T LC/MS (Final).[/COLOR] He has posted numerous labs stating he normally has high SHBG in the 60-70 nmol/L range. These are his labs from 4/2019. As you can see his TT is 972 ng/dL, SHBG was not tested? but from other labs posted he usually runs high 60-70 nmol/L and Albumin 4.3 g/dL (mean) and his FT 30.62 ng/dL (reference range 5.00-21.00 ng/dL).....so even with a high SHBG 60-70 nmol/L his FT is over 3/4 the top end of the reference range. [ATTACH=full]8648[/ATTACH] Now if we take those numbers and use the TruT calculated method.....albeit the reference ranges are on a different scale. Mind you we do not have know his SHBG but will use the higher end number of 70 nmol/L as he usually has SHBG in the 60-70 nmol/L range. TT 972 ng/dL, SHBG 70 nmol/L, Albumin 4.3 ng/dL (mean) than his FT is 30.25 ng/dL (reference range 16-31 ng/dL).....so even with a high SHBG of 70 nmol/L his FT is almost top end of the reference range. [ATTACH=full]8647[/ATTACH] Now again as you can see when he tested FT using Equilibrium Dialysis his FT 30.62 ng/dL (reference range 5.00-21.00 ng/dL).....is over 3/4 the top end of the reference range. Again we have no idea what his SHBG level was when he had lab work done but he is very well know to have high SHBG as he has stated many times let alone show in lab work he has posted previously. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
FT using TruT vs Dialysis methods
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