Daily Anastrozole

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Defy Medical TRT clinic doctor
If a guy actually NEEDED that much, symptoms were out of control, then yes the plausible part of a daily AI is the half-life of Anastrozole is appx ~50hrs so twice per week. Timing it up with the shots interval is were you can get the twice per week the thought being T rises and E follows so you take it with your shots, or the following day.
 

Cataceous

Super Moderator
Some guys have said they feel better with daily dosing. I'm doing daily now and I can't say I notice much difference from when I was doing EOD.
 

DragonBits

Well-Known Member
Some guys have said they feel better with daily dosing. I'm doing daily now and I can't say I notice much difference from when I was doing EOD.


That's quite a turn of events, if I am not mistaken didn't you once post you were taking estrogen to increase your E2?
 

Cataceous

Super Moderator
That's quite a turn of events, if I am not mistaken didn't you once post you were taking estrogen to increase your E2?
Yes, during an unusual period of undetectable estradiol that occurred when I paused use of hCG. Estradiol seemed to be rebounding to normal—high—levels even before I resumed hCG. I have gone for long periods without an AI and estradiol in the 50s pg/mL. The symptom of excess emotionalism was kind of interesting, but I eventually got tired of it and started micro-dosing anastrozole. This puts estradiol in the 30s, still higher than the 0.3% of testosterone mentioned by Nelson.
 

DragonBits

Well-Known Member
Yes, during an unusual period of undetectable estradiol that occurred when I paused use of hCG. Estradiol seemed to be rebounding to normal—high—levels even before I resumed hCG. I have gone for long periods without an AI and estradiol in the 50s pg/mL. The symptom of excess emotionalism was kind of interesting, but I eventually got tired of it and started micro-dosing anastrozole. This puts estradiol in the 30s, still higher than the 0.3% of testosterone mentioned by Nelson.

In the normal course of TRT, I usually have E2 around 2.5%. Clomid got me up to 5.7%. I have seen 1.7% and 4 %. I have tried several different variations of TRT, combining t cream with nebido, so it's hard to say what is "normal". I even tried mico-dosing anastrozole, 1/2 of a 0.125 tab every other day for about 3 weeks after an injection.

But I think in the future I will keep it simple.
 
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