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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Brain estrogen creation 'critical to maintain full sexual activity or desire in males'
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<blockquote data-quote="Nelson Vergel" data-source="post: 186914" data-attributes="member: 3"><p>There is evidence in some studies of this:</p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/high-estradiol-boosts-libido-in-men-on-testosterone-therapy.1666/[/URL]</p><p></p><p>"In 2013, Finkelstein <em>et al</em>. looked at the effects of testosterone and estrogen on male sexual function. <strong>They found that the administration of testosterone with and without aromatase inhibitors markedly impaired sexual function when aromatization was inhibited.<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854098/#ref18" target="_blank">18</a> In addition, a study by Ramasamy <em>et al</em>. in 2014 showed that libido was increased in men receiving TST when testosterone levels were >300 ng dl-1 and estradiol levels were >5 ng dl-1. Most compelling is the fact that in men with serum testosterone <300 ng dl-1, sexual drive was seen to be markedly higher when estradiol levels were >5 ng dl-1.<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854098/#ref19" target="_blank">19</a> In addition, when patients with low testosterone were treated with letrozole, a potent aromatase inhibitor, libido was decreased, suggesting that complete elimination of estradiol and decreasing the T/E ratio too severely, adversely affects sexual desire in men</strong>.<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854098/#ref20" target="_blank">20</a> These studies provide evidence that both estrogen and testosterone are necessary for normal libido in testosterone-deficient men. Clinically, the dependence of libido in hypogonadal men on both testosterone and estrogen indicates that a cautious approach to the use of aromatase inhibitors is warranted and that the T/E ratio has an impact. It might be reasonable that while prescribing TST one should monitor the levels of both testosterone and estrogen and their relationship to each other. "</p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/estradiol-in-men-libido-and-brain-function.14388/[/URL]</p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 186914, member: 3"] There is evidence in some studies of this: [URL unfurl="true"]https://www.excelmale.com/forum/threads/high-estradiol-boosts-libido-in-men-on-testosterone-therapy.1666/[/URL] "In 2013, Finkelstein [I]et al[/I]. looked at the effects of testosterone and estrogen on male sexual function. [B]They found that the administration of testosterone with and without aromatase inhibitors markedly impaired sexual function when aromatization was inhibited.[URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854098/#ref18']18[/URL] In addition, a study by Ramasamy [I]et al[/I]. in 2014 showed that libido was increased in men receiving TST when testosterone levels were >300 ng dl-1 and estradiol levels were >5 ng dl-1. Most compelling is the fact that in men with serum testosterone <300 ng dl-1, sexual drive was seen to be markedly higher when estradiol levels were >5 ng dl-1.[URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854098/#ref19']19[/URL] In addition, when patients with low testosterone were treated with letrozole, a potent aromatase inhibitor, libido was decreased, suggesting that complete elimination of estradiol and decreasing the T/E ratio too severely, adversely affects sexual desire in men[/B].[URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854098/#ref20']20[/URL] These studies provide evidence that both estrogen and testosterone are necessary for normal libido in testosterone-deficient men. Clinically, the dependence of libido in hypogonadal men on both testosterone and estrogen indicates that a cautious approach to the use of aromatase inhibitors is warranted and that the T/E ratio has an impact. It might be reasonable that while prescribing TST one should monitor the levels of both testosterone and estrogen and their relationship to each other. " [URL unfurl="true"]https://www.excelmale.com/forum/threads/estradiol-in-men-libido-and-brain-function.14388/[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Brain estrogen creation 'critical to maintain full sexual activity or desire in males'
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