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Health & Wellness
Brain-derived estrogen and neural function
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<blockquote data-quote="madman" data-source="post: 212633" data-attributes="member: 13851"><p><strong>Fig. 6. <u>Cognitive functions regulated by neuron-derived E2 (NDE2) and the commonly used behavioral tests for rodent studies</u>. Neuron-derived E2 (NDE2) is critical for hippocampus-dependent spatial reference memory, which is often tested using the Barnes Maze test. Hippocampus-dependent recognition memory is another important cognitive function that is regulated by NDE2 and which can be assessed using the Novel Object Recognition Test (NORT). In addition, NDE2 was also demonstrated to regulate contextual, but not cued fear memory, which can be evaluated using Fearing Conditioning Test. Finally, NDE2 is essential to prevent depressive-like behavior in female mice, which can be tested with the Forced Swimming Test.</strong></p><p><strong>[ATTACH=full]17922[/ATTACH]</strong></p></blockquote><p></p>
[QUOTE="madman, post: 212633, member: 13851"] [B]Fig. 6. [U]Cognitive functions regulated by neuron-derived E2 (NDE2) and the commonly used behavioral tests for rodent studies[/U]. Neuron-derived E2 (NDE2) is critical for hippocampus-dependent spatial reference memory, which is often tested using the Barnes Maze test. Hippocampus-dependent recognition memory is another important cognitive function that is regulated by NDE2 and which can be assessed using the Novel Object Recognition Test (NORT). In addition, NDE2 was also demonstrated to regulate contextual, but not cued fear memory, which can be evaluated using Fearing Conditioning Test. Finally, NDE2 is essential to prevent depressive-like behavior in female mice, which can be tested with the Forced Swimming Test. [ATTACH type="full"]17922[/ATTACH][/B] [/QUOTE]
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Brain-derived estrogen and neural function
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