Blood test- Low SHBG, High E2 (over range), High DHT (top end of range).... any thoughts?

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BillyJ03z

Active Member
I'm on Test Prop @ 15mg ED SQ and Armour Thryoid 3 grains.

For the past 2 1/2 months, I have noticed my hair is rapidly thinning and dry, my beard/stache seems to be growing slower looking mildly sparcer and not as dark.... Energy, mood, libido and sleep sucks... I suspected high E possibly among possibilities.

Just got my labs back ....

Estradiol, by TMS

51.6 pg/mL

10.0 - 42.0 pg/mL

H


5 A DIHYDROTESTOSTERONE

652.3 pg/mL

106.0 - 719.0 pg/mL


Sex Hormone Binding Globulin

20 nmol/L

11 - 80 nmol/L


DHEA Sulfate

138.3 mcg/dL

24.0 - 690.0 mcg/dL


Testosterone, Free Male

149.0 pg/mL

47.0 - 244.0 pg/mL


Testosterone, Total Male

531.4 ng/dL

300.0 - 890.0 ng/dL



*Thyroid supplementation raises my SHBG to 20's from the chronic single digits induced by TRT and puts all my Lipids/Cholestrol in range(Lipid Panel has always been bad since on TRT). Pre-TRT my SHBG was 30-37 and Lipids were good. TRT definitely drives down my SHBG and destroys my lipids.


Since I'm low SHBG, does high E2 take a priority over DHT giving me the issues I described above?


-Regardless of what the Test/FT lab shows I have already reduced Test prop to 10mg ED SQ.
-started ADEX @ .25 @ 3 x WK (temporary) just to get E2 down and will reassess at new test dose.
-started Oral Preg 30mg in morning (trying to backfill pathways from TRT)
-started Oral DHEA 10mg at night (I am sensitive to DHEA, took 25 to 50mg in past drove E2 over 100, but it did put my DHEA to the 50-60% range)
-started Progesterone cream 20mg on head (thinning spots) 3 x wk (hoping it regulates DHT bring a little lower)
 
Last edited:
Defy Medical TRT clinic doctor

Match

Member
Maybe some aromatase inhibitor can help reduce E. I think low SHBG also contributes to the symptoms, so that High Free T is not always ideal in that case
 
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