Blood test for HCG ??

[DragonBits]

HCG Beta Subunit, Quantitative (Cancer) Blood Test

This test is used as a tumor marker for certain cancers. It is used to evaluate and monitor male individuals with testicular tumors. This test is also used to determine the presence of hCG in individuals with gestational trophoblastic disease.

Quantitative HCG Beta Subunit | Blood Test - Life Extension

Beta HCG (quantitative) blood test is used as a tumor marker for certain cancers.

www.lifeextension.com

So if I am taking HCG, would it show up with this sort of blood test?

 

[Cataceous]

Probably it will show up, though typical doses are near the detection limit if it's the same test Dr. Saya used for his case studies:

What is the best dose of HCG? Dr Saya presents two case studies.

Community - I am sharing and have attached the write-up of a recent small case study I have conducted on quantitative serum beta hCG concentrations relating to hCG injections. This study is limited to dosages of 150iu and 500iu, although I hope to obtain more data in the near future. P.S...

www.excelmale.com

 

[Nelson Vergel]

This is actually the important test besides sperm count https://www.discountedlabs.com/17-oh-progesterone-hcg-efficacy-predictor

 

[DragonBits]

This is actually the important test besides sperm count 17 - OH Progesterone : HCG + TRT Efficacy Predictor

Nelson, I use progesterone cream in the evening, do you think this might affect the results?

The test assay is measuring 17-hydroxyprogesterone which is NOT the same as progesterone but is similar, I was wondering if this might confuse the results.

 

[he-man100]

Nelson, I use progesterone cream in the evening, do you think this might affect the results?

The test assay is measuring 17-hydroxyprogesterone which is NOT the same as progesterone but is similar, I was wondering if this might confuse the results.

Progesterone has a cross reactivity of 1,2% with the 17oh Progesterone assay.

https://www.drg-diagnostics.de/files/cla-4665_ifu--17oh-progesterone.pdf

 

[Nelson Vergel]

It would be so cool to see if progesterone actually increases 17-OH-progesterone enough for intratesticular testosterone to normalize without hCG. I have an intuition that it may not accomplish that even though we see it upstream of 17-OH-PROG.

But that 17, 20 lyase is a tricky enzyme that very few people have researched deeply except for cases of deficiencies.

Cytochrome P450 17α Hydroxylase/17,20 Lyase (CYP17) Function in Cholesterol Biosynthesis: Identification of Squalene Monooxygenase (Epoxidase) Activity Associated with CYP17 in Leydig Cells

Abstract. Cytochrome P450 17α-hydroxylase/17,20-lyase (CYP17) is a microsomal enzyme catalyzing two distinct activities, 17α-hydroxylase and 17,20-lyase, e

academic.oup.com

Private message me. I would love to help you get the test while you are on progesterone cream and then after a washout period.

Are you also on hCG and TRT?

What benefits have you had from transdermal progesterone? Better sleep?

 

[DragonBits]

Progesterone has a cross reactivity of 1,2% with the 17oh Progesterone assay.

https://www.drg-diagnostics.de/files/cla-4665_ifu--17oh-progesterone.pdf

Thanks, that isn't a big cross reactivity.

 

[DragonBits]

It would be so cool to see if progesterone actually increases 17-OH-progesterone enough for intratesticular testosterone to normalize without hCG. I have an intuition that it may not accomplish that even though we see it upstream of 17-OH-PROG.

View attachment 10445


View attachment 10447
But that 17, 20 lyase is a tricky enzyme that very few people have researched deeply except for cases of deficiencies.

Cytochrome P450 17α Hydroxylase/17,20 Lyase (CYP17) Function in Cholesterol Biosynthesis: Identification of Squalene Monooxygenase (Epoxidase) Activity Associated with CYP17 in Leydig Cells

Abstract. Cytochrome P450 17α-hydroxylase/17,20-lyase (CYP17) is a microsomal enzyme catalyzing two distinct activities, 17α-hydroxylase and 17,20-lyase, e

academic.oup.com

Private message me. I would love to help you get the test while you are on progesterone cream and then after a washout period.

Are you also on hCG and TRT?

What benefits have you had from transdermal progesterone? Better sleep?

Currently, I just started using HCG again, but it's only been 3 times in the last 2 weeks, 500 IU.

I have been on TRT for 11 years now, with a 3 year break starting 5/2015 to increase fertility as my wife wanted to get pregnant. My testosterone declined to 326 ng/dl after quitting, then with clomid it increased to 470 ng/dl and sperm counts increased to normal. Likely my baseline testosterone is 320-380 without any TRT.

I can't say for sure progesterone helps with anything, my sleep is erratic, some nights it is great, most nights I get up constantly. It seems after ~5 am I sleep much better, but that kind of ruins my day to sleep to 9AM. I am pretty sure initially I was taking too much progesterone as I was getting dizzy during the day and sleepy all day long. After cutting back I did two blood tests, both came back with a 0.5 on a ng/ml 0-0.5 scale, so top of that range with a reduced level of progesterone, i estimate I was taking ~22 mg which was probably the dose recommended for women, I cut back to ~6.77 mg, maybe I will increase it a little. Or maybe take it earlier.

For me, four things are a "problem" that I am keep searching for ways to correct.

1) My LDL is a little high, like 98-150. it's been that way since time began, or 1992 in my testing history.

2) PSA is a little high, 3.2-5. it bounces around, the most recent test was 4.15. (All prostate cancer type tests I took indicate very low likelihood of cancer) just an enlarged prostate with no signs yet of BPH. I don't think there is anything I can do to reduce the size / psa level and at some future date I will likely get a medical intervention to reduce prostate size.

3) Sleep is a tough nut to crack, I make progress but still no ironclad protocol for that.

4) Another problem is I am 68 and keep getting older!