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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Are high total T levels dangerous?
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<blockquote data-quote="madman" data-source="post: 192256" data-attributes="member: 13851"><p>Herein lies the issue.</p><p></p><p>Although TT is important to know FT is what truly matters as it is the active unbound fraction of testosterone responsible for the beneficial effects.</p><p></p><p></p><p>You stated that: </p><p></p><p><span style="color: rgb(184, 49, 47)">Ive been on trt 6 years. On this very small amount of testosterone I've had <u>total T labs ranging from 957-2200 ng/d</u>l.</span></p><p><span style="color: rgb(184, 49, 47)"></span></p><p><span style="color: rgb(184, 49, 47)"><u>Most of the time my total T is off the chart while my free T hangs out in the mid to high teens</u>. Rarely has my free T hit the 20+ ng/dl level.</span></p><p></p><p>Without posting labs we have absolutely no idea where your SHBG has sat when you were running a TT 957-2200 ng/dL as you only posted the most recent lab which shows an absurdly high SHBG 105 nmol/L.</p><p></p><p>Even more concerning is where your FT level truly sat on such protocol and unless you had your FT tested using the most accurate assay such as the gold standard Equilibrium Dialysis or Ultrafiltration then I would not rely on the results.</p><p></p><p></p><p></p><p></p><p><span style="color: rgb(184, 49, 47)">25 mg cypionate every 3.5 days</span></p><p><span style="color: rgb(184, 49, 47)">500 iu hcg 2x a week</span></p><p><span style="color: rgb(184, 49, 47)"><strong><u>.25 Anastrozole 3x a week</u></strong></span></p><p><span style="color: rgb(184, 49, 47)"></span></p><p><span style="color: rgb(184, 49, 47)">Ive been on trt 6 years. On this very small amount of testosterone I've had total T labs ranging from 957-2200 ng/dl.</span></p><p></p><p>Even then the protocol you have been put on is horrible and with such a low weekly dose of T (50 mg split 25 mg every 3.5 days + 500 iu hCG every 3.5 days), I would find it hard to believe that anyone could achieve a healthy FT level (upper end) and top it off with the fact that you are using an AI.....go figure!</p><p></p><p>How could anyone with high SHBG feel-good on such protocol?</p><p></p><p>Post any labs with reference ranges and the assays used to test your TT/FT?</p><p></p><p>If your FT was not tested using an accurate assay then you would be wise to get it done.</p><p></p><p></p><p></p><p></p><p>The most accurate assay for TT (LC-MS/MS) and FT (Equilibrium Dialysis or Ultrafiltration).</p><p></p><p>Especially in cases of altered SHBG, I would not rely on any other testing method other than ED or UF when it comes to testing free testosterone.</p><p></p><p></p><p>Use Nelsons DiscountedLabs.</p><p></p><p></p><p>Any of these will suffice: <span style="color: rgb(184, 49, 47)">(kill 2 birds with one stone)</span></p><p><span style="color: rgb(184, 49, 47)"></span></p><p><span style="color: rgb(184, 49, 47)">1 </span>[URL unfurl="true"]https://www.discountedlabs.com/hematocrit-total-and-free-testosterone-1500-ng-dl[/URL]</p><p></p><p><span style="color: rgb(184, 49, 47)">2 </span>[URL unfurl="true"]https://www.discountedlabs.com/hematocrit-total-and-free-testosterone-1500-ng-dl[/URL]</p></blockquote><p></p>
[QUOTE="madman, post: 192256, member: 13851"] Herein lies the issue. Although TT is important to know FT is what truly matters as it is the active unbound fraction of testosterone responsible for the beneficial effects. You stated that: [COLOR=rgb(184, 49, 47)]Ive been on trt 6 years. On this very small amount of testosterone I've had [U]total T labs ranging from 957-2200 ng/d[/U]l. [U]Most of the time my total T is off the chart while my free T hangs out in the mid to high teens[/U]. Rarely has my free T hit the 20+ ng/dl level.[/COLOR] Without posting labs we have absolutely no idea where your SHBG has sat when you were running a TT 957-2200 ng/dL as you only posted the most recent lab which shows an absurdly high SHBG 105 nmol/L. Even more concerning is where your FT level truly sat on such protocol and unless you had your FT tested using the most accurate assay such as the gold standard Equilibrium Dialysis or Ultrafiltration then I would not rely on the results. [COLOR=rgb(184, 49, 47)]25 mg cypionate every 3.5 days 500 iu hcg 2x a week [B][U].25 Anastrozole 3x a week[/U][/B] Ive been on trt 6 years. On this very small amount of testosterone I've had total T labs ranging from 957-2200 ng/dl.[/COLOR] Even then the protocol you have been put on is horrible and with such a low weekly dose of T (50 mg split 25 mg every 3.5 days + 500 iu hCG every 3.5 days), I would find it hard to believe that anyone could achieve a healthy FT level (upper end) and top it off with the fact that you are using an AI.....go figure! How could anyone with high SHBG feel-good on such protocol? Post any labs with reference ranges and the assays used to test your TT/FT? If your FT was not tested using an accurate assay then you would be wise to get it done. The most accurate assay for TT (LC-MS/MS) and FT (Equilibrium Dialysis or Ultrafiltration). Especially in cases of altered SHBG, I would not rely on any other testing method other than ED or UF when it comes to testing free testosterone. Use Nelsons DiscountedLabs. Any of these will suffice: [COLOR=rgb(184, 49, 47)](kill 2 birds with one stone) 1 [/COLOR][URL unfurl="true"]https://www.discountedlabs.com/hematocrit-total-and-free-testosterone-1500-ng-dl[/URL] [COLOR=rgb(184, 49, 47)]2 [/COLOR][URL unfurl="true"]https://www.discountedlabs.com/hematocrit-total-and-free-testosterone-1500-ng-dl[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Are high total T levels dangerous?
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