ExcelMale
Menu
Home
What's new
Latest activity
Forums
New posts
Search forums
What's new
New posts
Latest activity
Videos
Lab Tests
Doctor Finder
Buy Books
About Us
Men’s Health Coaching
Log in
Register
What's new
Search
Search
Search titles only
By:
New posts
Search forums
Menu
Log in
Register
Navigation
Install the app
Install
More options
Contact us
Close Menu
Forums
Testosterone Replacement, Low T, HCG, & Beyond
Clomid for PCT, fertility or low T
anyone with experience using mesterolone (proviron) to combat SHBG rise from clomid?
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Reply to thread
Message
<blockquote data-quote="Aki" data-source="post: 244193" data-attributes="member: 14084"><p>I'm not sure I totally follow. But just to "think out loud" here:</p><p></p><p>If you mean (with me trying to phrase it in a drastically simplified way) that the body tries to maintain a certain level of free-T (said level being determined by genetics, environment, health, lifestyle, etc. and thus sometimes not optimal for one's needs) and other sex hormones like SHBG and total T get regulated in order to maintain that, then that does sound reasonable. With this notion in mind, two possible ways of increasing free-T are: "hijacking the HPTA" (i.e. TRT) and "tricking the body into producing more free-T" (something like clomiphene that blocks estrogen receptors). Personally, I'm only interested in the latter, as TRT is not something I consider an option right now. The problem is to make the body reach a more "acceptable" value of free-T, whether that be best achieved by lowering SHBG, or decreasing the rate of aromatisation, using an LH mimic, etc.</p><p></p><p>I think the challenge is that the body appears to "resist" such changes and manipulating some hormones will cause fluctuations in others to try to undo our attempts, until some uneasy equilibrium is reached.</p><p></p><p>Anyway, I've really run with this line of thinking, so forgive me for blathering on. <img src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" class="smilie smilie--sprite smilie--sprite1" alt=":)" title="Smile :)" loading="lazy" data-shortname=":)" /></p><p></p><p>I should mention that my SHBG values are really "out of the range" high at the moment, not just modestly elevated - assuming the lab ranges are meaningful.</p></blockquote><p></p>
[QUOTE="Aki, post: 244193, member: 14084"] I'm not sure I totally follow. But just to "think out loud" here: If you mean (with me trying to phrase it in a drastically simplified way) that the body tries to maintain a certain level of free-T (said level being determined by genetics, environment, health, lifestyle, etc. and thus sometimes not optimal for one's needs) and other sex hormones like SHBG and total T get regulated in order to maintain that, then that does sound reasonable. With this notion in mind, two possible ways of increasing free-T are: "hijacking the HPTA" (i.e. TRT) and "tricking the body into producing more free-T" (something like clomiphene that blocks estrogen receptors). Personally, I'm only interested in the latter, as TRT is not something I consider an option right now. The problem is to make the body reach a more "acceptable" value of free-T, whether that be best achieved by lowering SHBG, or decreasing the rate of aromatisation, using an LH mimic, etc. I think the challenge is that the body appears to "resist" such changes and manipulating some hormones will cause fluctuations in others to try to undo our attempts, until some uneasy equilibrium is reached. Anyway, I've really run with this line of thinking, so forgive me for blathering on. :) I should mention that my SHBG values are really "out of the range" high at the moment, not just modestly elevated - assuming the lab ranges are meaningful. [/QUOTE]
Insert quotes…
Verification
Post reply
Share this page
Facebook
Twitter
Reddit
Pinterest
Tumblr
WhatsApp
Email
Share
Link
Sponsors
Forums
Testosterone Replacement, Low T, HCG, & Beyond
Clomid for PCT, fertility or low T
anyone with experience using mesterolone (proviron) to combat SHBG rise from clomid?
This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register.
By continuing to use this site, you are consenting to our use of cookies.
Accept
Learn more…
Top