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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Allosterically coupled multi-site binding of T to human serum albumin
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<blockquote data-quote="madman" data-source="post: 189998" data-attributes="member: 13851"><p><strong>Figure 1: <span style="color: rgb(184, 49, 47)">Synthesis schema and NMR analysis of labeled testosterone upon binding to HSA.</span> <span style="color: rgb(44, 130, 201)">(A) </span>Chemical synthesis schema for [13C]-labeled testosterone. A sharp doublet is observed in the testosterone solution. The resonances shift downfield in the presence of HSA and change multiplicity to a multiplet splitting pattern, denoting multiple interaction environments for HSA-bound testosterone. <span style="color: rgb(44, 130, 201)">(B)</span> 13C NMR spectral overlay of 1 mM [13C]-T and 1 mM [13C]-T in the presence of 0.5 mM HSA</strong></p><p>[ATTACH=full]11376[/ATTACH]</p><p>[ATTACH=full]11377[/ATTACH]</p></blockquote><p></p>
[QUOTE="madman, post: 189998, member: 13851"] [B]Figure 1: [COLOR=rgb(184, 49, 47)]Synthesis schema and NMR analysis of labeled testosterone upon binding to HSA.[/COLOR] [COLOR=rgb(44, 130, 201)](A) [/COLOR]Chemical synthesis schema for [13C]-labeled testosterone. A sharp doublet is observed in the testosterone solution. The resonances shift downfield in the presence of HSA and change multiplicity to a multiplet splitting pattern, denoting multiple interaction environments for HSA-bound testosterone. [COLOR=rgb(44, 130, 201)](B)[/COLOR] 13C NMR spectral overlay of 1 mM [13C]-T and 1 mM [13C]-T in the presence of 0.5 mM HSA[/B] [ATTACH type="full"]11376[/ATTACH] [ATTACH type="full"]11377[/ATTACH] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Allosterically coupled multi-site binding of T to human serum albumin
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