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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
A SERM (fispemifene) increases testosterone but not sex drive
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<blockquote data-quote="John O'Connor" data-source="post: 35833" data-attributes="member: 13064"><p>Interesting pharmacological effect. Do most estrogen blockers also act specifically at the level of the pituitary? I know testosterone is converted to estrogen, thus the common need for aromatase inhibitors, but didn't know blocking estrogen would cause testosterone to increase. If anyone can explain this, I'd love to understand it. </p><p></p><p><a href="http://www.apricusbio.com/pipeline/fispemifene/" target="_blank">http://www.apricusbio.com/pipeline/fispemifene/</a> </p><p>"Fispemifene acts in secondary hypogonadism by inhibiting the negative feedback of testosterone production via an estrogen-blocking effect at the level of the pituitary, resulting in increased testosterone production in the testes"</p></blockquote><p></p>
[QUOTE="John O'Connor, post: 35833, member: 13064"] Interesting pharmacological effect. Do most estrogen blockers also act specifically at the level of the pituitary? I know testosterone is converted to estrogen, thus the common need for aromatase inhibitors, but didn't know blocking estrogen would cause testosterone to increase. If anyone can explain this, I'd love to understand it. [url]http://www.apricusbio.com/pipeline/fispemifene/[/url] "Fispemifene acts in secondary hypogonadism by inhibiting the negative feedback of testosterone production via an estrogen-blocking effect at the level of the pituitary, resulting in increased testosterone production in the testes" [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
A SERM (fispemifene) increases testosterone but not sex drive
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