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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
62 Year Old Male - Latest Blood Work - Comments Please
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<blockquote data-quote="jacb" data-source="post: 215702" data-attributes="member: 18836"><p>Thanks Nelson</p><p></p><p>You say "<em><strong>The "normal" range of estradiol does not apply in men on TRT with higher total T levels. This study showed how the body adjusts how much estradiol to produce to compensate for the higher T.</strong></em>"</p><p></p><p>"<a href="https://www.excelmale.com/forum/threads/how-to-predict-estradiol-and-dht-at-different-testosterone-doses.20830/" target="_blank">How to Predict Estradiol and DHT at Different Testosterone Doses</a>".</p><p></p><p>You/the article makes the point that it is the ratio between Total Testosterone and Estradiol that we should primarily be concerned about, not the absolute pg/mL value. It goes without saying that more Testosterone we have, the greater the amount of Estadiol we will have because of the aromatase process.</p><p></p><p>The article also says that the efficiency of the aromatase process changes as we age and this is shown in a range of graphs. So it is now possible to accurately predict Estradiol and DHT values if we know the Total Testosterone and the age of the man.</p><p></p><p>Like you, I made a small spread sheet up with the given data. I then input my measured values to see how closely my actual data matches the predictions.</p><p></p><p>I see that in my case I make somewhere between 20/25% more E2 than the predicted value. At the moment I am reducing my weekly dose of Test Cyp to 110mg per week with the hope that my TT levels will stabilize around 800 pmol/L and a Free T value of 30 ng/dL. I will retest in three months time.</p><p></p><p>Acording to the calculated E2 prediction (considering my age and TT of 800 pmol/L) the E2 will be 48.7 pg/mL.</p><p></p><p><strong>My question for you is how far from the target values are "acceptable" before considering Ai intervention? The same question stands for the TT/E2 ratio etc.</strong></p><p><strong></strong></p><p><strong>I predict that at TT of 800 pmol/L my E2 will be approximately 48.7 + 23% (based on my test records to date) = 58.4 pg.mL If I am correct would that be something you would be concerned about for a 62 year old man with a TT of 800 pmol/L, concerned enough to intervein with Ai?</strong></p><p></p><p>Of course I will do nothing until I have the test results in three Months time.</p><p></p><p>Regards</p><p></p><p>[ATTACH=full]19223[/ATTACH]</p><p></p><p></p><p></p><p>.</p></blockquote><p></p>
[QUOTE="jacb, post: 215702, member: 18836"] Thanks Nelson You say "[I][B]The "normal" range of estradiol does not apply in men on TRT with higher total T levels. This study showed how the body adjusts how much estradiol to produce to compensate for the higher T.[/B][/I]" "[URL='https://www.excelmale.com/forum/threads/how-to-predict-estradiol-and-dht-at-different-testosterone-doses.20830/']How to Predict Estradiol and DHT at Different Testosterone Doses[/URL]". You/the article makes the point that it is the ratio between Total Testosterone and Estradiol that we should primarily be concerned about, not the absolute pg/mL value. It goes without saying that more Testosterone we have, the greater the amount of Estadiol we will have because of the aromatase process. The article also says that the efficiency of the aromatase process changes as we age and this is shown in a range of graphs. So it is now possible to accurately predict Estradiol and DHT values if we know the Total Testosterone and the age of the man. Like you, I made a small spread sheet up with the given data. I then input my measured values to see how closely my actual data matches the predictions. I see that in my case I make somewhere between 20/25% more E2 than the predicted value. At the moment I am reducing my weekly dose of Test Cyp to 110mg per week with the hope that my TT levels will stabilize around 800 pmol/L and a Free T value of 30 ng/dL. I will retest in three months time. Acording to the calculated E2 prediction (considering my age and TT of 800 pmol/L) the E2 will be 48.7 pg/mL. [B]My question for you is how far from the target values are "acceptable" before considering Ai intervention? The same question stands for the TT/E2 ratio etc. I predict that at TT of 800 pmol/L my E2 will be approximately 48.7 + 23% (based on my test records to date) = 58.4 pg.mL If I am correct would that be something you would be concerned about for a 62 year old man with a TT of 800 pmol/L, concerned enough to intervein with Ai?[/B] Of course I will do nothing until I have the test results in three Months time. Regards [ATTACH type="full" alt="E2 Prediction.JPG"]19223[/ATTACH] . [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
62 Year Old Male - Latest Blood Work - Comments Please
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