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  1. K

    Permanent ED from tamoxifen?

    Hello. So my doctor gave me tamoxifen for low t and I only took 5 pills (20mg) eod. Didn’t help with the symptoms only gave me severe loss of libido, ed and anhedonia. Then we changed to sustanon 250mg every 10 days. My doctor said symptoms of tamoxifen will go away in “couple of weeks” And I...
  2. Pnw0031

    Raising SHBG using raloxifene

    Curious if anyone has raised shbg using a SERM like raloxifene, a new blood test shown my shbg was even lower- 11! It’s likely my shbg was lowered via Proviron given to me by my endo (she is an idiot but that’s besides the point). I do have some raloxifene I’d like to use to raise my shbg to...
  3. J

    Trying to do a HPTA restart with my doc…29 days in my total T is only 18:(

    My labs are attached. Total T is only 18, and free T is only .3!!! Okay have no libido whatsoever. My dick gets hard, but I have no interest in using it, and I don’t orgasm at all. I was on TRT for nearly 2 years, and tried to come off recently. I stopped my test Cypionate injections 29 days...
  4. B

    Standalone SERM as monotherapy??

    Hey guys (and Admins) I'm looking for some pick me up. I'm 44 and have lowish test; my libidio and work drive are down these last few years. Will a standalone SERM help?? I'm a 2 times a week gym goes. 6'2 230lb ex athlete. I've never done anything more than protein powder before. I've...
  5. H

    SERM instead of HCG for TRT

    I have read some posts about the possibility of using a SERM like clomid or tamoxifen instead of HCG in order to keep tests functioning while on TRT. I did an experiment and just wanted to post my results (take the information as is and hopefully it helps to answer some questions you might...
  6. Nelson Vergel

    A SERM (fispemifene) increases testosterone but not sex drive

    Shares of San Diego-based Apricus Biosciences were crushed this morning after the biotech reported that its experimental testosterone-boosting drug had failed both the primary and secondary endpoints in a Phase IIb study among men with secondary hypogonadism and sexual dysfunction. And the...
  7. R

    The endocrinologist's guide to managing self-treating patients

    Male Central Hypogonadism Secondary to Exogenous Androgens Clin Endocrinol. 2015;82(5):624-632. In this paper a group of clinicians acknowledges that practitioners are encountering an increasing number of patients seeking help with recovery from self-administered anabolic steroids. [...
  8. Nelson Vergel

    A New SERM to Raise Testosterone : Fispemifene

    SAN DIEGO, June 1, 2015 (GLOBE NEWSWIRE) -- Apricus Biosciences, Inc. (Nasdaq:APRI), a biopharmaceutical company advancing innovative medicines in urology and rheumatology, today announced that it has begun enrolling patients in a Phase 2b clinical trial to evaluate Apricus' novel product...
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