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  1. C

    Tips for lowering Norepinephrine levels?

    Hey guys, I wanted to ask if anyone has any tips on lowering norepinephrine levels. I read a thread in regards to doxazosin here on EM, I don’t have a PCP to ask in regards to an Rx to attempt, and I also fear that being only 28 and attempting to ask for this script I would get rejected. So I...
  2. K

    Effect on Bloods when Quitting Nicotine on TRT

    Hey Excelmale, I'm curious if anyone has successfully quit nicotine while dialed in on TRT and has before and after bloods to show any changes in serum levels? Nicotine supposedly acts as a mild anti aromatase inhibitor and is said to also INCREASE SHBG which is not in my favor considering I...
  3. W

    Hangover Libido

    Normally I have low libido, weak erections, sensitivity issues, delayed ejaculation and if I do get off, I'm only good for onetime. My refractory period is a few days. It's more like the mental part of my libido is just not there. I don't drink a lot but If I do go out for a night of drinking...
  4. S

    TRT and Neurotransmitter Balance

    What effects, if any, does TRT have on neurotransmitters, particularly on serotonin? I know that in the initial stages of TRT, there is a pronounced effect on dopamine - I have been told that this is what causes the "honeymoon" that many guys experience. Are there neurotransmitter imbalances...
  5. T

    Neurotransmitter testing

    So I've been on TRT a few years. Tried injections, creams, HCG, AI's, DHEA, pregnenalone, and various combination of them all. I never really found the silver bullet I was looking for. By all accounts, my hormones are at optimal levels but my libido is very low and erections are so so with...
  6. Dr. John Crisler

    We Know Estrogen is a Sex Hormone, But is it Also a Neurotransmitter?

    My pal Dr. Mark Gordon just sent me this: Is brain estradiol a hormone or a neurotransmitter? - PubMed This may explain why T gels are better for treating sexual dysfunction; they provide much more variability throughout the day. This would be in addition to increasing DHT more than shots...
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