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  1. H

    Primary, secondary or mixed both?

    Hello guys, what do you think, is this secondary or primary hypogonadism, or both in mixed? Ran couple bloodworks, months between them. Went to the Urology who checked my testicles they were small-normal(borderline arthropy) and soft. Then i went to the testicle ultrasound and they ultrasounded...
  2. F

    Considering TRT for Accutane related hormonal changes

    Hi guys, I’m Frank from western Europe and I’m new on this forum. I hope you can share your ideas/experiences about HRT after Accutane. My story: I took Accutane in 1999 (40mg a day / 5 months). The drug greatly reduced my libido and gave me some mental issues like lower mood, anxiety and...
  3. madman

    Low Testosterone (Hypogonadism) Lecture

  4. I

    Afraid to start TRT. Could you share your experience?

    Before I describe my problem, I wanted to say hello to everyone on this forum. I recently started reading it, and I learned a lot of valuable things. I’m 29 years old now and about 4-5 years ago, I started to feel worse, weakened, have libido problems, poor results in the gym, unhappy, etc...
  5. C

    RF9: May it be a new therapeutic option for hypogonadotropic hypogonadism?

    Intriguing stuff, possibly highlighting another distinct cause of hypogonadism, along with a new treatment option. There's been little discussion of gonadotropin-inhibitory hormone or GnIH. This hormone counters kisspeptin and suppresses the HPTA. An excess of GnIH may lead to hypogonadism. RF9...
  6. J

    To TRT or to not TRT. Testosterone Enanthate + HCG

    Hi I've read hundreds of posts related to testosterone and hcg dosages, but I can't make my mind due to all the contradictory info found on how to approach my TRT therapy. Some background: 38 yo male, low libido, anxiety, brain fog, moderate-severe depression, difficulty to gain muscle mass -...
  7. D

    Hypopituitarism and muscle gains

    Hello everyone, I am a 32 year-old man. I have suffered from hypopituitarism since birth. At the age of 5 I started taking GH and Hydrocortisone. The pediatrician monitored my bone development until I was 17 years old, when she decided that I should stop the GH replacement therapy and start...
  8. J

    Hypogonadism in HIV Positive Men

    This is a review article discussing the treatment of hypogonadism in HIV positive men, with a discussion of several cases. The full text of the article is available online. The introduction says: "Hypogonadism commonly affects HIV-positive men and is associated with a variety of clinical...
  9. B

    Is low Estradiol (Naturally) along low free T effectively hypogonadism?

    I was reviewing blood tests from back when I was still natural in 2016. Total T in the 800s, single digit free T (pg/mL), E2 around 10 pg/mL. Then I started using steroids for about 18 months, hopped off. Total T in the 600s, free T and E2 around 12 pg/mL. I’m 10% fat year round. I’ve tried...
  10. S

    Hypogonadism and Low Estrogen

    Is it common to have Hypogonadism with Low Estrogen in males?
  11. E

    Nebido users In the UK- Read this please

    Hi to all, Is there anyone using Nebido in the UK? We are doing a research about this drug and need to talk to guys with experience on it. Please, read all the details in the link provided. There is an incentive of 540£ for 2 hours face to face interview plus 30 min pre-task. Help me to...
  12. DragonBits

    The Long Haul: Treating Men with Obesity with Testosterone

    The Long Haul: Treating Men with Obesity with Testosterone BY DEREK BAGLEY JUN 2019 A study presented at ENDO 2019 shows that long-term testosterone therapy in men with obesity and hypogonadism can actually contribute to prolonged weight loss without an added risk for mortality or major...
  13. D

    Etiology: What do you think caused your low T (hypogonadism)?

    Hey everyone, I had a though and felt I'd ask everyone. What do you think caused your hypogonadism? I was thinking about my etiology and realized I don't particularly have one. I did have an one sided orchiectomy (removal of testicle) for cryptorchidism, but that wouldn't have an effect on my...
  14. S

    Hypogonadism (Low Testosterone) or Depression - How to Differentiate

    There are many common symptoms in depression and hypogonadism, especially those subjective, my question is how do physicians know when hypogonadism causes depression, and when depression causes hypogonadal symptoms?
  15. K

    Do I Have Primary or Secondary Hypogonadism or is it Thyroid?

    To be clear, my doctor's never diagnosed me as hypgonadal because my Total Testosterone has never been below 300. However, I'm 42 years old and for at least of a handful of times over the years in my 30's I have never tested over a 396 in my Total T. I've consistently been in the 323-396 range...
  16. J

    31 y/o newbie, Low Free Test, Looking for some advice

    Hi guys So, I’ve read a number a number of posts across multiple TRT forums, and I feel like I’ve learnt a lot, but equally feel like I’ve opened up a huge can of worms! I recently had a blood test to confirm a long-held belief of mine; that I had low testosterone. I’m now at a decision...
  17. 3

    Vasectomy possible cause of low T?

    I just read a response to a thread on another site and someone mentioned that their Vasectomy killed their T levels. I almost jumped out of my chair! I had never thought about it, my V just happens to coincide with my first experience of low T symptoms (some ED - which I NEVER had before my...
  18. S

    Primary/Secondary Hypogonadism?

    Hi all, This is my very first post on a newly created account. Sorry, it might be a long post. I've been dealing with a lot. Since June of 2017, I've been doing a lot of research on men's health on the internet. I've been dealing with a myriad of symptoms regarding testosterone for...
  19. A

    25 year old male - hypogonadism

    Hi, I’m Andrew, 25 year old male. I just wanted anyone’s opinion on my current situation and any advice. (I’m very overweight but doing something about currently) I have known for many years that I was no way near finishing puberty. But put it down to being overweight and a late bloomer. I’ve...
  20. T

    Primary Hypogonadism and TRT to Secondary Hypogonadism with HCG

    Hi Guys, I am from the UK and have a long story.. I was wrongly diagnosed as having primary hypogonadism in December 2015. I was put on TRT 250mg Sustanon every 3 weeks. I also have osteoprosis which was confirmed by a dexa scan. I went to see a Urologist privatetly regarding fertility in May...
  21. C

    [Question] Frequent Urination + Hypogonadism (crashed E2)

    Hello, to give a little info about myself, I am currently 6'1 at 200lb, 28y/o. I had blood work done back in the beginning of March and my levels were 2120.8 Test, and >50 Free test. ALT was 47 and creatine was a bit high but nothing uncommon. I ran 2 cycles back to back, with no breaks, which I...
  22. Nelson Vergel

    Psychiatric Issues and Low Mood Caused by Hormone Problems

    Review Article Psychiatric Manifestations of Endocrine Disorders Full Paper: Psychiatric Manifestations of Endocrine Disorders ADRENAL: CUSHING’S SYNDROME AND ADDISON’S DISEASE Over the past few decades, a number of authors have found a significant amount of psychological disorders...
  23. X

    Frustrated by Docs: Might TRT Make Sense?

    Hey guys quick story. (Not listing all labs from past because 5 years worth) Overweight whole life. 6ft tall, Got up to 300lbs in college first year, by 3rd year dropped to 185lbs with diet and lots of exercise (RAN 18mi/week+ weights) lots of greens and protein. Life was GREAT! Met a girl! Fell...
  24. T

    HCG Protocol

    I was diagnosed with low T in November when I had a count of 236. After reading a book and gaining some knowledge, then realizing that my doctor was not going to test my estradiol (I asked) and was only interested in getting me above 300, I decided to change doctors. I found a doctor in San...
  25. D

    Suggestions for TRT

    Dear all, I have been suffering from low T since childhood. My doctor gave me TRT long time back for around 2 years but then he stopped. Currently my levels are around 150-250. I feel depressed without any reason, less motivation and feel tired all the time. I need some advice, what should be...
  26. M

    Tamoxifen to TRT?

    Does anyone have experience with tamoxifen? I suspect hypogonadism. My testosterone is low. My pituitary gland is ok and my testes are as well.
  27. V


    Hello, Going to provide a brief summary. 52 year old Hypogonadic male with ED, etc. Had bilateral microsurgical varicocelectomy to remove varicose veins which I had for 20 years. Idiot doctors should have had me have the procedure long ago but GP's and general urologists are idiots. Now my...
  28. B

    Glad to be here!

    Hi, I'm married to the BugMan and will be posting more frequently than he. (got more time, I like the computer more than he does, and have more medical experience!). We both have been on and off the Testosterone replacement bandwagon. He's read here quite a bit in the past, so we thought it...
  29. R

    Short Course: Pathology of the Endocrine Module (Axis)

    https://www.uthsc.edu/endocrinology/documents/ch08-syllabus-Childress.pdf This 2010 course intended for UT health sciences students of Dale Childress MD is a decent reference material and a fairly easy read for the advanced layman. excerpt: 'Both neural input from the central nervous system...
  30. L

    Started hcg after 3 years of 200 mg of cyp weekly

    Doctor has me on 2000ius twice a week to jump start sperm production. Wondering thoughts on this as its been about 6 weeks now and my testicles aren't to much bigger than when i was on trt. Also tired as hell almost like a dead person most of the time.
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