1. R

    Raise Testosterone with Anastrozole

    Is it possible to increase testosterone level with only Anastrozole? If a person is not on TRT.
  2. F

    Hard only at the end

    Anyone know what it means or what it is indicative of when the penis is semi hard through sex or masturbation and then ends up getting erect right before climaxing and during. Low E? high E? This happens sometimes while other times it works fine..
  3. J

    Best zinc to lower estrogen levels? Zinc picolinate?

    Hi everyone, In the past, I used to supplement with zinc nitrate. However, I recently heard that zinc picolinate may be better while being on TRT. Would you guys recommend zinc picolinate over zinc nitrate to lower estrogen levels? My estrogen is not too high at the moment, but my dr recently...
  4. C

    High E2 on latest labs

    Looking for some advice please. Current Protocol 100mg 2x weekly 500iu HCG 2x weekly No AI (Discontinued. It was 1mg 2x weekly and I felt it gave me mood swings) Latest Labs Total Testosterone >1500 E2 69pg/mL Notes: I'm not sure if the E2 test was sensitive or not, the labs don't show...
  5. Z

    Letting e2 run wild

    My old dr was a dr who was all about not treating E2. He said let it go as high as you want and it won’t be a problem. Well I am seeing a new dr now and my e2 sensitive was 45. My libido has been super low, my anxiety kind of high, also my junk shrivels up to nothing along with my scrotum...
  6. DragonBits

    New thoughts on sleep

    I don't think this has ever been discussed, but it might be important for those of us that often wake up from sleep. Oral contraceptive contain estrogen and progestin, (progestin is an analog of progesterone) which have been shown to increase the elimination half life of caffeine from 5-6 hours...
  7. DragonBits

    Estrogen Synthesis Leads Prostatic Inflammation (Prostatitis)

    Increased Endogenous Estrogen Synthesis Leads to the Sequential Induction of Prostatic Inflammation (Prostatitis) and Prostatic Pre-Malignancy Stuart J. Ellem,* Hong Wang,* Matti Poutanen,† and Gail P. Risbridger* Prostatitis causes substantial morbidity to men, through associated urinary...
  8. R

    5 mg daily dosage of Cialis and estrogen levels

    I have a question in regard to estrogen levels on Test cypionate and Hcg combination with the use of 5 mg of Cialis daily. For those using 5 mg of Cialis how much would you say that Cialis has lowered your estrogen levels as compared to when you did not use it on the same protocol?
  9. A

    How bad is this T:E ratio?

    So I inject 100mg weekly and I’m about to split my dose but until then I got my bloods back and e2 was high. I’m curious about how off this ratio is though? 2 days after injection T is 1066. 4 days post injection T is 865 and E2 ultrasensitive is 59pg/ml. I’m waiting on trough results.
  10. A

    High e2 on 100mg

    I take 100mg once a week just got my sensitive e2 back 4 days after my shot and it was 59 range is less than 29. My Test level hasn’t come back yet but I’m freaking out because it explains why I’ve been breaking out. I could only imagine what my e2 is at the day after my shot. Should I split my...
  11. C

    Brain estrogen creation 'critical to maintain full sexual activity or desire in males'

    A tip of the hat to "PakMan" at PeakT for the reference to this article. The underlying work is on mice, but may have implications for humans. Summary: Researchers have uncovered specific regions of brain tissue where aromatase is present, that drives male sexual desire. Aromatase converts...
  12. B

    It is Estrogen or DHT that causes BPH?

    It is the Estrogen or DHT that make men have problens in prostate when get older or by hormones use? Older guys on trt here, please share if you are having problems with it. I want to understand about this subject.
  13. R

    Lump Under nipple but low estradiol.

    I’ve been on TRT for about a year now and taking test 200 cyp @ .4 2x a week along with HCG @ 500 iu’s 2x a week. Started taking anastrazole .125 2x a week about 8 weeks in because a lump develop under nipple. Took tamoxifen, started anastrazole and it cleared up. Fast forward approx 6-8 months...
  14. D

    Estrogen Blocker or not when taking TRT/HCG

    I have been on TRT for 15 years. I am waiting for my HCG prescription to arrive and feel comfortable adding that to my regimen. Since my doctor is not an Endocrinologist, he is prescribing Estrogen blockers and TRT. My question is if I take TRT/HCG, do I still need the estrogen blocker? I...
  15. V

    Strange case at my clinic

    Greetings, I have a TRT patient at my clinic and the fellow providers nor myself can figure this out. I have a patient who had a total Estrogen level of 20,240, with a TT of 420 and FT of 12. I had the other provider to run sensitive estradiol on him and he is pitifully low at 3.4, I had them...
  16. T

    Daily Injections and blood work irregularities

    Hi everyone, first post but have greatly appreciated everyone’s comments on the forum that I have been reading through. I am having some frustration getting my protocol dialed in. Started TRT 1.5 years ago and have been using Testosterone Cypionate and all injections SubQ. Blood work and dosage...
  17. T

    Quest Diagnostics - Estradiol Range is Inadequate

    See attached. I recentlay had bloodwork done, and my Ultrasensitive Estradiol came back at a 4. Typically, I would say this is low, however, they showed a range of <29. Accroding to them this was in the “Green” zone, and I am good to go. I am not buying it. What are your thoughts? I wasn’t...
  18. T

    Estrogen - Ejaculation

    Question - has anyone found there to be a correlation between the amount of fluid released during ejaculation, and estrogen levels?
  19. J

    Low T a Risk Factor for Covid-19

    A study evaluated the risk factors of men admitted to a hospital in Germany for Covid-19 and found that one factor is low testosterone levels. This run contrary to recent discussion in the media where it has been argued that testosterone raises the risk for Covid-19. The preprint is on MedRxiv...
  20. michaelser88

    Something went really wrong...need some help

    Hi Guys! I hope somebody can help in my situation because i really dont understand what happened and what i have to do.. :/ So my story: I made a big mistake last year november i did 2 month hcg monotherapy, that means eod 200iu hcg... I noticed pain in my breast... It develoled gyno.. I tried...
  21. A

    Role of Estrogen in Human Thyroid function

    Role of Estrogen in Human Thyroid function The purpose of this post is to tell you that too much estrogen has a profound affect on not just Thyroid Binding globulin but also thyroid function in general. This could be from endogenous sources,plastics,or as in one study it was meat with heavy...
  22. R

    Looking for TRT docs in Toronto

    I'm 60. Been on TRT about 9 months. I almost non existent sex drive, difficulty maintaining erections. Local GP and several endocrinologists all said basically I need TRT but my tests were not quite low enough, nothing they could do legally. One told me to go to a local gym, find the biggest guy...
  23. G

    Does Pregnenolone and/or DHEA raise testosterone or estrogen levels?

    I’m curious as I have just begun taking 25mgs Pregnenolone from Empower pharmacy daily. I might be crazy but when I started DHEA I think my testosterone levels went up slightly. I’m wondering if I’ll have to lower my daily testosterone injection dose. Any thoughts or personal experience would be...
  24. J

    Why the Coronavirus Seems to Hit Men Harder Than Women...Estrogen Levels?

    Maybe one more reason to let your Estrogen levels rise when doing TRT. Although men and women have been infected in roughly equal numbers, researchers found, the death rate among men was 2.8 %, compared with 1.7% among women.... could Estrogen levels be the key to the difference? Link To...
  25. B

    Muscle weakness and joint pain.

    Hello, I used To be a avid bodybuilder now on trt (20mg daily test enanthate no ai). A symptom I’ve been dealing with for awhile is muscle weakness and joint pain. My muscles are fatigued easily (they burn right away from exertion) and my muscle contractions are poor (there soft even when...
  26. T

    Started Nandrolone.

    Hello Everyone, I've posted here a few times, and I've been following for a little over a year. I've really struggled to feel good on test since my first three week honeymoon on cream ended. The struggle seems to be E related and I will pass through days with good results, but for the most...
  27. S

    Any Dangers in Skipping a Few Days of Progesterone?

    My wife and I are traveling for the next 5 days. She takes Estrogen cream nightly and 50mg of Progesterone. She packed the estrogen but left the progesterone on the table. Just wondering if anyone knows if its safe to skip the progesterone for 5 days and just take the Estrogen. Conversely she...
  28. L

    AI side effects?

    I had a question regarding the side effects of AI’a and can’t seem to find a consistent consensus regarding side effects. I am aware that there can be side effects from the usage of AIs, from my understanding the sides are from crashing estradiol to an unhealthy level. Most of the negatives...
  29. K

    In a mild panic, did I just OD on anastrazole?

    So, funny story. (For those that aren’t me lol) I keep my Arimidex on the left, viagra on the right. Evidently during cleaning my wife swapped them not knowing. I took 3 and thought man, I’m getting low. (I wasn’t but hindsight - wrong bottle) so I’m aware the dosage for full blown cancer...
  30. K

    Are Estrogen Levels in Men Increasing in Recent Decades Due to Environmental and Other Causes?

    We know that men in the modern age are bombarded with estrogens and estrogenic chemicals from every direction in food, water, medications, environment, and products. Which leads me to wonder: what is actually an acceptable testosterone and estrogen level for men? Testosterone levels have been...
  31. T

    Stopped my AI...

    Good Morning Everyone, I've been using an AI at various doses over the last year for estrogen management without much success. 12 days ago, I stopped taking my AI, and I don't really feel any better or worse. I am on the emotional side, but that happened occasionally while taking the AI. I...