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  1. W

    Possible edema? Side-effect management?

    So I recently was put on this TRT routine: Begin T Cyp 200 mg/ml – 0.25 ml inject IM/SQ three time weekly Begin HCG 350 iu inject SQ three times weekly Begin Anastrozole 0.25mg by mouth three times weekly Begin DHEA 25 mg by mouth at night My first week I was feeling great. Within one month, I...
  2. Nelson Vergel

    Nandrolone Increases Aldosterone Concentration and Serum Na+/K+ : Reasons for Bloating ?

    This study used nandrolone in animals. I bet this could translate to humans that experience water retention on TRT or anabolic steroids. Increased aldosterone causes water and sodium retention and high blood pressure. Effect of Administration of Nandrolone Decanoate upon Aldosterone...
  3. Nelson Vergel

    Water Retention Caused by Testosterone May Have Nothing to Do with Estradiol

    I get a lot of emails from men on testosterone replacement therapy (and/or HCG) that feel they have water retention (some with ankle swelling) and they are puzzled that their estradiol is low or below 35 micrograms/ml. They may have tried anastrozole treatment without any success in decreasing...
  4. Nelson Vergel

    Water Retention Caused by Anabolics and Testosterone

    I think Patrick Arnold makes a great point about a potential mechanism for edema that has nothing to do with elevated estradiol. People familiar with the use of anabolic steroids know that water retention and hypertension (high blood pressure) are potential side effects. This is due to the fact...
  5. Nelson Vergel

    Testosterone induced water retention: Guide to Natural Diuretics

    I would like to find out if anyone has tried herbal diuretics. 15 Natural Diuretics: Herbs, Supplements, Foods, and Drinks There are a few on Amazon with good reviews: Amazon.com Amazon.com Amazon.com
  6. J

    edema[swelling] what is the cause

    Started to get a lot of swelling in my legs and 6 pound weight gain over 4 days after being on TRT for 5weeks. No other symptoms. Is this a side effect of the TRT or the estradiol breakdown product. Got some relief with an over the counter diuretic. any other suggestions?
  7. Nelson Vergel

    Ankle swelling after starting testosterone injections

    I got this question from a friend of mine today who started testosterone replacement 3 weeks ago (injections of 100 mg per week): "I've been gaining a lot of weight. Does this mean my estradiol is high? I don't have any nipple soreness or severe bloating but my ankles and wrist are swelling."...
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