e2

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  1. R

    AI's and joint pain

    Everything I've found online for forever regarding AI's and joint pain basically says that it is most likely due to low E2. I've been using Exemestane for a while now, and have basically been keeping my E2 at 40 and above, and I am having joint pain in a couple of areas. Being that my E2 is...
  2. T

    E2 went a little low from one Arimidex dosing

    Yesterday I took a very small amount of arimidex 0 (0.125mg) when I shouldn’t have. My e2 has dipped a bit too low. Fortunately it’s not crashed, but it’s enough to be annoying. I have a slightly dry eyed feeling, worsened anxiety and low motivation. My sexual function is still pretty decent, so...
  3. M

    Opinions on E2 management.

    On TRT for just over 4 years. Lately I've been part of a facebook group that also has a youtube channel: https://www.youtube.com/c/FoxPowerBasement They are all things TRT, however a very strong theme of the group is that NOBODY needs an AI. EVER. So for the past 6 months or so I have not...
  4. R

    Could this be low E2?

    About a month ago I got my second Pfizer covid shot. I felt a little sick for about four days. I recovered, but I noticed a few days later that my joints don't feel right. I googled and saw a lot of cases of this being a lingering effect from the vax, so I figured there's not really much I could...
  5. B

    High e2 and high shbg

    Hey guys new member here! So I finished up my clomid a little over a week ago and got bloods done. I know it was too soon, but I felt really shitty. Estradiol-Ultrasensative 56 (<or29 pg/ml) SHBG 54 (10-50 Nmol/L) Total test 1526 (250-1100) Free test 241 (35-155) I feel pretty shitty...
  6. E

    Always thirst, kinda dry mouth

    Would you say E2 related?
  7. Mr_Ree

    Blood test results (advice)

    Hello. I’m 36 yrs old. I‘m a bodybuilder and have been a blast and cruise guy for the last 4 years. I’ve been on TRT for the last 10 months after ending a pretty hefty blast cycle. my TRT dose has been 300mg/week up until results came back then back down to 200mg/week. I did supplement HMG or...
  8. B

    Raloxifene for High E2?

    Start out with a brief history. Im 56 type 1 diabetic. Have been for 53 years. Been on TRT for 5 years has improved my overall blood glucose and I have sex drive again. 3 years ago i found a pretty good TRT Doc. I'm in Idaho and choices are limited. Last summer 2021 he handed me off to a...
  9. R

    Low e2 symptoms for a long time

    Hey everyone I have a huge problem with estradiol. I am constantly tormented by symptoms of low estradiol. I have not taken any IA since December. I am currently taking 100 mg test prop e2d. My mood came back for a while, but continued poping joints and being flat. I decided to hit 2500iu hcg...
  10. T

    4 weeks off TRT - still needing AI to combat E2 anxiety

    Hey guys, Looking to get some input. I am 34 years old, low SHBG (17-19), 160lb, athletic build. I've spent the last year experimenting different protocols to find one where I feel good/normal. Surprisingly, the closest I can get to feeling fine is on a single injection frequency, with AI every...
  11. M

    Could progesterone use crash estrogen or cause joint pain?

    Hello, for the past 2 weeks I’ve been using progesterone cream, one pump scrotal application per day. Over this weekend I started to notice my joints were achy, felt sort of dry, popping a bit. I’ve actually been feeling pretty good (libido and mentally) but thinking I may have overdone it with...
  12. J

    HCG DOSE FREQUENCY

    Hi everybody. I would like to hear from people having experience (or having knowledge) on different hcg dose frequency protocols. Basically I want to know if every day lower dose has any different outcome, better o worse, compared to every other day, every 3 days, twice weekly etc. I mean, same...
  13. G

    Fish Oil and SHBG

    I can't find the pubmed study at the moment, but it's all over Google if searched. Apparently, fish oil lowers SHBG. I'm wondering how drastic this effect could be and if cutting my EPA/DHA dose from 2.4g to 1.2g may let it rise. I've read on here that guys with low SHBG have harder times...
  14. B

    Test Prop @ 15mg ED/SQ vs Test Cyp @ 20mg ED/SQ... Results.....

    Below are my Lab results from my use of Test Cyp @ 20mg ed/SQ for 8 months and Test Prop @ 15mg ed/sq for about 3 months. Test Cyp @ 20mg ED/SQ (8 months) Testosterone Total-Male 609.0 ng/dL 300.0 - 890.0 ng/dL Free Testosterone 168.7 pg/mL 47.0 - 244.0 pg/mL Estradiol, Serum 72...
  15. C

    What is considered optimal Estradiol, Ultrasensitive range?

    I think the other day I may have taken too much AI and crashed my E2 cuz had numb cock and no libido and Viagra had almost no effect. 2 days later I took Estradiol blood test and Estradiol Ultrasensitive LC/MS blood test. The results… Estradiol = 21 (Range: < OR = 39) Estradiol Ultrasensitive...
  16. X

    Titrating down: advice please

    Dear all. Hope you're all well. I was wondering if I might tap into some of the great knowledge of you guys. Thanks to this forum, I recently decided to titrate my dosage of 160mg (test cyp) down to a more "sensible" level where I don't need to use an AI, and still get the benefits of TRT. On...
  17. B

    E2 has jumped dramatically in the last couple of years, age related?

    My dose has stayed the same at 200mg a week for the last decade, and my e2 sensitive was usually in the low 60s which was fine with me But the last e2 sensitive test came back at 107! This is a huge jump considering the dose and the injection schedule has remained unchanged over that period. I...
  18. L

    Help! Advice before AI (Anastrozole)

    So I've been on TRT for a number of months, and can't seem to get dialed in. I feel lethargic, emotional/mild depression, no drive/motivation, low libido, weak erectile function. Doctor seems a bit flustered and asked what I think the issue is. After all my research, the only thing I can come up...
  19. M

    Anyone used/using calcium d glucarate for estrogen control?

    I've been reading a lot of good things lately about calcium d glucarate particularly in it's effectiveness of estrogen control. Just wondering if anyone on here has used it and can share their thoughts on it?
  20. G

    Help: T and E too high, I'm red etc.

    Hi all, I've been on TRT a little over a year. Started at 100mg a week; was tested a month in and numbers were still low so i was bumped to 150mg a week. I was tested about 6 weeks after the increase and my total t and free t were considered "optimal" - I believe total was right around 1000 and...
  21. M

    Could DIM have knocked my e2 too low?

    Current Protocol: 110Mg pw Test Cyp Injecting E2D I've always only needed a very small amount of anastrozole. Having seen Dr Crisler and others talk about using DIM (Diindolylmethane) for years, I decided I would give this a try instead of the anastrozole. I've been taking 200mg of DIM (100mg...
  22. J

    Do these look like results from a sensitive e2 test?

  23. W

    Anyone supplementing estrogen?

    It's pretty much the only hormone that I haven't tried. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854098/
  24. D

    Anyone feels better on less frequent injections? for ex.: e7d vs e3.5d

    So I have a lot of trouble dialing in my TRT. Started gel with low T of 260 ng/dl and <5 E2 (non sensitive) , undetectable. SHBG of 23. Felt like HELL. started androgel, felt the best i have ever felt in life after 4 days, this lasted for 1.5 weeks then I lost all my benefits and slowly became...
  25. T

    Sensitive E2 in the 100’s

    Was looking for input from some of the moderators/experienced users. I work in hormone optimization/peptides/ED management/primary care. First, huge thanks to this forum, Nelson and others who have been instrumental in advancing my understanding of TRT and how to engage in optimization versus...
  26. L

    TRT low, minimal E2 suggestions

    New user, long time lurker reading up. I'm a 42 yr old male, and I was diagnosed primary hypo around 2012. Ive been on TRT for 8+ years or so. Im using 100mg every 7 days IM. My question is, is it typical for my E2 to be in the lower range? My last test result was 13.1 in the range of 8.0...
  27. U

    I found a TRT protocol that works

    So after trying injections for 2.5 years I went back to testosterone pellets. I'm one week in and my libido is already coming back strong. I started on pellets 6 years ago and stayed on them for 3 years and they always worked great. I stopped them because every now and then I'd have one that...
  28. A

    Any evidence of Resveratrol lowering E2?

    Some have recommended Resveratrol to me as a means to lower E2 naturally. Has anyone had success lowering E2 a few points with resveratrol? I want to lower my e2 by 5-10 pg/mL
  29. T

    Sensitive to E2 - subq and HCG

    Hi guys, I'm very sensitive to medium to medium high E2. I feel like absolute shit, depressed, anxious, low libido. I talked to a new doctor who wants to put me on subq test Cyp and HCG: As far as I understand there's more aromatase in the fat, and so I'd think I would aromatise more with...
  30. A

    High e2 on 100mg

    I take 100mg once a week just got my sensitive e2 back 4 days after my shot and it was 59 range is less than 29. My Test level hasn’t come back yet but I’m freaking out because it explains why I’ve been breaking out. I could only imagine what my e2 is at the day after my shot. Should I split my...
  31. S

    List of compounds that have a propensity to aromatize to estradiol.

    I recently came across a thread where someone (@Cataceous ?) posted a nice chart showing many different compounds, family, propensity to aromatize to E2. Can’t find it now. If anyone could find it based on my vague description, I’d appreciate it!
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