1. C

    Brain estrogen creation 'critical to maintain full sexual activity or desire in males'

    A tip of the hat to "PakMan" at PeakT for the reference to this article. The underlying work is on mice, but may have implications for humans. Summary: Researchers have uncovered specific regions of brain tissue where aromatase is present, that drives male sexual desire. Aromatase converts...
  2. A

    Long term use of AI

    Hi, Has anyone used Aromatase Inhibitor for long time? I would like to know whats your thought on this? What are the side effects. It would be helpful if there is no serious side effects for low shbg guys. FYI: I am on low TRT dosage and I am trying to avoid AI but just wondering if anybody...
  3. D

    Myomin and Other Natural AIs

    What's up guys, Anyone have any experience using Myomin as a natural AI? I have seen some members use it here and there but not many accounts of running it all of the time. Seems to be effective from the reviews on Amazon and even seeing that some TRT doctors are recommending it first before...
  4. D

    The answer to high levels of aromatase?

    Hi all, Long time reader, first time poster. I've just come across some research which I don't believe has been discussed on here previously, and after posting in the TRT Australia group, thought certain members of this forum might find this interesting/useful. Background: 26 yrs old Lean...
  5. Nelson Vergel

    HCG, Clomid, and Anastrozole Use in Male Infertility

    New article: Click here
  6. S

    Why some men are high aromatizers - looking past the most common factors!

    Reduce your body fat, keep your diet clean and don't drink too much beer. If all those are in order you should not have problems with high estrogen. This is the reasoning we all have heard. I saw an internist a few weeks ago who said that by looking at my body type, there's no possibility for me...
  7. Nelson Vergel

    Men with high estradiol have stronger bones but more fat and less muscle

    Eur J Endocrinol. 2015 Aug;173(2):167-74. High aromatase activity in hypogonadal men is associated with higher spine bone mineral density, increased truncal fat and reduced lean mass. Aguirre LE Abstract OBJECTIVE: Because the aromatase enzyme catalyzes the conversion of testosterone to...
  8. Nelson Vergel

    Scientists report that enzyme that alters testosterone to estrogen has big impact in healthy brain

    Another reason not to mess with your aromatase activity (Most of you know my opinion about how many men on TRT are overdosing anastrozole when most do not even need it) "An enzyme that converts testosterone to estrogen appears to have significant impact in a healthy and injured brain...
  9. Nelson Vergel

    Vitamin D is anti-estrogenic where it's needed

    Vitamin D is anti-estrogenic where it's needed According to an animal and cell study that endocrinologists at Stanford University published in Endocrinology, the active form of vitamin D – calcitriol [structural formula shown below] – is an anti-oestrogen. The study is interesting...
  10. S

    Zinc and Aromatase

    In my first post I stated that my estadiol was less than 5 and my T was 502. I have been taking a zinc supplement faithfully for years, 25 to 50mg per day. Does anyone think that this is what could have pushed my estradiol so low by blocking the conversion of T to estroge ? Also as I have...