1. F

    Does Anyone Feel Better on an AI?

    I know this topic has been beaten to death and with a little legwork, I am sure to find dozens of threads on this, so I apologize. But, like many here, I am still perplexed on why most forms of TRT I have tried cause side effects that outweigh the benefits. I have a ton of posts out there, but...
  2. L

    Help! Advice before AI (Anastrozole)

    So I've been on TRT for a number of months, and can't seem to get dialed in. I feel lethargic, emotional/mild depression, no drive/motivation, low libido, weak erectile function. Doctor seems a bit flustered and asked what I think the issue is. After all my research, the only thing I can come up...
  3. D

    switching clinics to get away from test/anastrazole mixture and Gonadorelin

    Hello all, I am a 32 year old male 6'-1" and 190 pounds. semi-athletic build with probably around 15% body fat and exercise regularly. Lifestyle over the last year: I lift weights 5 times a week and run about 6 miles per week. I have a pretty good diet and get plenty of sleep usually 8-10 hours...
  4. R

    Controlling estrogen

    What is a good way to control estrogen when anastrazole is too powerful? I was taking 80 mgs of testosterone 2 x a week when my estrogen went through the roof. I started taking .125 mgs of anastrazole 2 x a week and it brought my estradiol down to an 8 and total test was at 854. Can anastrazole...
  5. J

    High estradiol even on anastrazole

    I'm on a morphine pump for chronic back pain and my testosterone dropped to 190. For two years I've been on 1 mg of testosterone cypionate weekly (ships from Empower Pharmacy) and donate blood regularly to keep my hematocrit/hemoglobin levels in check. Last year my estradiol levels were...
  6. S

    Once anastrozole reaches stead state, does E2 stay relatively constant all else equal?

    Assuming one is on anastrozole for a a few weeks, would the E2 levels stay relatively constantly all else equal or does it continue to drive E2 down over time? Basically what I'm asking is how long does one need to be on anastrozole to know if they are on the right dose?
  7. U

    I found a TRT protocol that works

    So after trying injections for 2.5 years I went back to testosterone pellets. I'm one week in and my libido is already coming back strong. I started on pellets 6 years ago and stayed on them for 3 years and they always worked great. I stopped them because every now and then I'd have one that...
  8. R

    Lump Under nipple but low estradiol.

    I’ve been on TRT for about a year now and taking test 200 cyp @ .4 2x a week along with HCG @ 500 iu’s 2x a week. Started taking anastrazole .125 2x a week about 8 weeks in because a lump develop under nipple. Took tamoxifen, started anastrazole and it cleared up. Fast forward approx 6-8 months...
  9. P

    How do I microdose Anastrozole?

    Hi fellows, I'm currently taking .125mg of Anastrozole 2x a week. I'd like up my dosage but not by a 50% and .125mg capsules are the smallest I can get and it's important I take them on certain days of the week as I try to match the peaks and valleys of my AI to my T levels. I use this...
  10. P

    How Much more Anastrozole when Starting HCG?

    Hi guys, I'm currently 150mg T/weekly (subQ) and feel really good. 2x a week I take 1 capsule of Anastrozole (.125mg). My labs all look really good (T, FT, E2, even progesterone). My gf and I want a kid and my doc has prescribed 500iu daily of HCG and then bump it up to 2000iu every other...
  11. R

    Advice on stopping or reducing AI?

    I'm on a 120mg test C, 2000ui HGC and 1 mg anastrozole a week split into two doses. Lab tests have historically been stable Total & Free test is around 1200 - 1300 Free test is around 24 -26 E2 is between 22 - 35 My Doc wants me to stop anastrozole. After all the touted benefits of estradiol...
  12. 5

    New guy, 10 mos. TRT, dosage/ED/libido questions

    Hey all - I've been on TRT for 10 months and just found this forum today - what a MASSIVE wealth of information! I've been relying on a single thread on another forum that's totally unrelated to health, and it's been a huge help, but nothing like this. I could really use your help today; TRT...
  13. K

    In a mild panic, did I just OD on anastrazole?

    So, funny story. (For those that aren’t me lol) I keep my Arimidex on the left, viagra on the right. Evidently during cleaning my wife swapped them not knowing. I took 3 and thought man, I’m getting low. (I wasn’t but hindsight - wrong bottle) so I’m aware the dosage for full blown cancer...
  14. B

    Please comment on my first TRT Protocol:

    After asking if the doc could split my dose into twice a week here is the protocol he recommended: Sunday evening: 75mg Test C taken intramuscularly Monday morning: .25mg HCG taken sub-Q Tuesday: 0.5mg Anastrozole Wednesday morning: 75mg Test C taken intramuscularly Thursday morning: .25mg HCG...
  15. A

    How Long to Feel Better Off AI??

    I was looking for the experiences of guys that have successfully gotten off of an AI. How long did it take to feel better? The anti-AI crowd swear with 100% certainty that your body “just needs to adjust”. Some say a couple weeks and some say a month or so. I have never been able to successfully...
  16. T

    Anastrazole and Arthritis

    My testosterone levels have been on the higher side since starting TRT. And after my last consultation with my doctor they suggested if I wanted to, I could try lowering my weekly injections from .45 ml twice a week of testosterone with .125 mg anastrazole 3x a 0.37 ml twice a week...
  17. T

    AI Troubles

    Guys... Need some help. When I'm high or low with estradiol I'm sensitive where I have a hard time with erections or get soft ones and have no penis sensitivity. Also I have low shbg which is between 13 and 17 depending when taken. My daily dose of test cyp is 30mg and hcg 300iu 2x per week...
  18. M

    Dialing In - Haematocrit & Estradiol Management

    Hey guys, I've been on TRT for about 9 months, and had a very positive experience thus far. Unfortunately, my most recent blood results indicated a couple of anomalies and I was hoping that some of the more knowledgable members here might be able to assist from a knowledge point of view. I've...
  19. A

    Anastrazole makes me so tired

    I took my first dose of 0.125mg yesterday and now it's like I've run a marathon. Have you guys had similar reactions? Does it stop after a while or is it persistent? I'm guessing the reason is that it can reduce red blood cell count and I, for genetic reasons, have low hemoglobin.
  20. D

    Poor response to TRT, looking for ideas

    I'm a 35 year-old with secondary hypo due to chronic illness. My symptoms are ED, fatigue, muscle pain, and low motivation. I hit a major obstacle when I became unable to take an AI due to adverse reactions, I'm now looking for other options. Here's a summary of my treatment: Clomid, 12.5-50...
  21. J

    Night sweats anxious and using anastrazole. Dosing guidance

    Hi guys, I know that the responses I’ll mostly get is to have my blood tested since it’s been 3 months or more. But I’ve been dealing with dialing in my levels for years now. So I’m looking for some general advice an insight before getting my labs done again. I’ve had to over the years split...
  22. C

    How potent is old Anastrazole?

    I ran out of my current prescription for Anastrazole and every day since Tuesday, I've been taking some three year old Anastrazole I had left over from another medical provider. I've read that medications generally lose potency as they age but most don't go bad. Does anyone know if three...
  23. P

    Exemestane vs Tamoxifen vs Anastrozole: How Much and How Often?

    Hi guys, My first post and grateful this site exists. I'm about to start TRT and don't get my labs back for a week. I had been on it before but discontinued when hospitalized for some stuff (unrelated and now gone). I'm going to start with 100mg a week of either equal parts (deca, cyp, eth...
  24. P

    Side effect (Feet Swelling) questions and AI

    47 year old male, overweight- High blood pressure and cholesterol, High A1c and IGF-1. Sleep apnea treated with CPAP for last 8 months. I started TRT back in August 2018. My primary care Dr. suspected low T after suspected Gynecomastia (later confirmed with Ultrasound & monogram). Low T was...
  25. W

    Clomid and AI (w/ low T & low E2)

    Summary of my lab work: Okay total T Low Free T High SHBG Low LH Underperforming Thyroid Low E2 Estradiol senstive - 7.4 (normal = 8.0 - 35.0) Doctor has started me on 12.5 Clomid (EOD) and AI (Anastrozole) (3x per week) From what I gather, the treatment plan lis designed to elevate my free T...
  26. B

    30 hours after first dose of hcg and ai violently ill!

    30 hours ago took first dose of hcg 400iu and anastrazole .125 bloating. Gas stomache pain and then finally violently ill puking until everything was out of me followed by extreme dry heaving for a couple minutes until i was sweating shaking pale and sweating. Mucus consistency chunks that...
  27. M

    Anastrazole and Exemestane

    Has anyone tried the peptides? How about good site to purchase tablets for cheap? Thanks.
  28. Z

    MWF protocol

    I just started this week on my new MWF 50mg each injection. The first week has been okay. I am going to avoid an AI if I can. I was just wondering if their are any members on here who do specifically 3 days a week and how it’s been going for them??? Thanks!
  29. Z

    New protocol

    So after going over labs today with my doctor. (Not going to post them, just because essentially from all the research I have done on this forum and others things seemed pretty normal.) I will just post the basics real quick tbiugh TT-917 E2 (ultra sensitive)-17 SHGB- 26 Prolactin- I can’t...
  30. Z


    Here are my labs, I just started seeing a new doctor. These labs are from last doctor awhile ago. My main reason for posting them though, is I am wondering just how much or how little my PA was testing for... thanks.
  31. J

    My Doctor Prescribed 1 mg Anastrozole Daily for High Estradiol

    I’m currently on Dr prescribed TRT at 200mg/week of Test C. My Estradiol is 104. My doctor prescribed 1mg of Anastrozole 2x week. Does this seem like a high dosage? Thanks