Hypogonadism (low testosterone) is common in chronic alcoholic men . Such hypogonadism has been shown to be due to alcohol toxicity occurring at the level of the testes as well as at the level of the hypothalamus and pituitary. Thus, in addition to reduced levels of plasma testosterone and a high prevalence of oligozoospermia. chronic alcoholic men frequently have concomitant “normal” or only minimally increased plasma levels of gonadotropins [follicle stimulating factor (FSH) and luteinizing hormone (LH)]
Low plasma testosterone values in men during hangover
Ethanol intoxication reduced testosterone and increased LH with no significant influence on estrogens, with more pronounced changes associated with hangovers
Ethanol intake at 0.675g/kg was able to enhance the testosterone-increasing response to injected gonadotropin-releasing hormone in healthy men.
Testosterone was increased in healthy women at an oral dose of 0.5g/kg ethanol, and this increase was more prominent in women using oral contraceptives
No significant influence on testosterone, adrenaline, or cortisol associated with alcohol intake after exercise
16 males consuming a large acute dose of vodka (2.2ml/kg 100-proof vodka within 15 minutes) noted suppression of testosterone after 84 minutes, with a spike in LH as well
An increase in cortisol and decrease in testosterone was seen by 12 hours after a large dose of alcohol, and small trends that reached significance at 36 hours were seen for LH and FSH in being increased.
Intake of a moderate amount of alcohol (30-40g) over a period of 3 weeks is associated with slightly suppressed testosterone levels in men only.
1g/kg ethanol was unable to significantly influence the endocrine parameters measured, but was able to reduce power output the next day
Low dose alcohol (0.5g/kg) was associated with a small (17%) increase in testosterone, which was abolished when the metabolism of ethanol was reduced
Special Reading: Exercise Increases Liver Enzymes