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    • Men with More Visceral Fat May Have Higher BPH risk

      Visceral adiposity index is associated with benign prostatic enlargement in non-diabetic patients: a cross-sectional study.

      To evaluate the association between visceral adiposity index (VAI) - a novel indicator for the assessment of visceral adipose tissue and prostate enlargement in non diabetic patients.

      Four hundred patients who were admitted to the Urology clinic between January and December 2014 with complaints of BPH(benign prostatic hyperplasia )/LUTS(male lower urinary tract symptoms)were enrolled in this cross-sectional study. Patients were divided into two groups according to their prostate volume and international prostate symptom score (IPSS) value. They were compared in terms of age, body mass index (BMI), VAI, prostate volume, PSA, post micturional residual volume (PMRV), uroflowmetry Q max value, triglyceride (TG), high density lipoprotein-cholesterol (HDL-C) and fasting blood sugar (FBS).

      Although univariate analyses reveal that age, BMI, waist circumference (WC), FBS, TG, HDL-C level and TG/HDL ratio were correlated with prostate volume, only age [1.125 OR (1.088-1.164), p = .00001], BMI [1.119 OR (1.040-1.204), p = .003], TG [1.043 OR (1.016-1.071), p = .002], HDL-C [0.923 OR (0.860-0.990), p = .025] and VAI [1.194 OR (1.110-1.305), p = .011] were statistically significant in multivariate analysis. A positive correlation was found between VAI value and prostate volume in the Spearman correlation test (r = 0.29, p = .00001). The calculated area under the curve (AUC) for prostate volumes of 30, 40 and 50 ml were 0.680 (0.621-0.738), 0.625 (0.570-0.681) and 0.590 (0.528-0.652), respectively.

      Our study revealed a positive correlation between VAI and prostate volume. Our results are needed to be tested with well-designed randomized prospective cohort studies.

      The aging male : the official journal of the International Society for the Study of the Aging Male. 2017 Aug 20 [Epub ahead of print]

      Huseyin Besiroglu, Emin Ozbek, Murat Dursun, Alper Otunctemur

      a Department of Urology , Catalca Ilyas Cokay State Hospital , Istanbul , Turkey., b Department of Urology , Istanbul Training and Research Hospital , Istanbul , Turkey., c Department of Urology , Bahcelievler State Hospital , Istanbul , Turkey., d Department of Urology , Okmeydani Training and Research Hospital , Istanbul , Turkey.

      PubMed http://www.ncbi.nlm.nih.gov/pubmed/28823197

      This article was originally published in forum thread: Men with More Visceral Fat May Have Higher BPH risk