madman
Super Moderator
ABSTRACT
Hypogonadism affects an extensive part of the male population, especially among the elderly. The quest for treatment regarding low levels of serum testosterone and male infertility has, therefore, worldwide relevance. Zinc has important biological actions insofar as the male reproductive physiology and endocrine system. In general, a common and safe recommendation for zinc in the treatment of male hypogonadism is 220 mg of zinc sulfate (equivalent to 50 mg of elemental zinc) twice a day, over one to four months. Additionally, it may be further required to extend, both the treatment, dose and daily fractionation of this mineral. Albeit medicinal doses of zinc may increase total testosterone and improve sperm count, the current body of evidence does not suggest broad recommendations regarding the use of zinc for all types of hypogonadism. In many cases, the use of zinc supplements is insufficient, with the use of surgery and drugs being required for an effective treatment.
Conclusion
The use of medicinal doses of zinc may be an option for male clinical cases that aim to increase testosterone and improve semen parameters. However, there is no consensus regarding the formula and amount of chelated zinc. Also, the optimal period of zinc administration related to the male hypogonadism treatment is currently unknown. Summarizing, an effective and safe posology widely used to increase serum testosterone concentrations and improve seminal parameters is 220 mg of zinc sulfate (equivalent to 50 mg of elemental zinc) twice daily for 1 to 4 months. Additionally, we propose that it may be required to extend the treatment, dose and daily fractionation of this mineral.
Hypogonadism affects an extensive part of the male population, especially among the elderly. The quest for treatment regarding low levels of serum testosterone and male infertility has, therefore, worldwide relevance. Zinc has important biological actions insofar as the male reproductive physiology and endocrine system. In general, a common and safe recommendation for zinc in the treatment of male hypogonadism is 220 mg of zinc sulfate (equivalent to 50 mg of elemental zinc) twice a day, over one to four months. Additionally, it may be further required to extend, both the treatment, dose and daily fractionation of this mineral. Albeit medicinal doses of zinc may increase total testosterone and improve sperm count, the current body of evidence does not suggest broad recommendations regarding the use of zinc for all types of hypogonadism. In many cases, the use of zinc supplements is insufficient, with the use of surgery and drugs being required for an effective treatment.
Conclusion
The use of medicinal doses of zinc may be an option for male clinical cases that aim to increase testosterone and improve semen parameters. However, there is no consensus regarding the formula and amount of chelated zinc. Also, the optimal period of zinc administration related to the male hypogonadism treatment is currently unknown. Summarizing, an effective and safe posology widely used to increase serum testosterone concentrations and improve seminal parameters is 220 mg of zinc sulfate (equivalent to 50 mg of elemental zinc) twice daily for 1 to 4 months. Additionally, we propose that it may be required to extend the treatment, dose and daily fractionation of this mineral.
