Transdermal HRT for Women: Best Bet for Lower VTE Risk

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Nelson Vergel

Founder, ExcelMale.com
When a blood clot breaks loose and travels in the blood, this is called a venous thromboembolism (VTE). The abbreviation DVT/PE refers to a VTE where a deep vein thrombosis (DVT) has moved to the lungs (PE or pulmonary embolism).

"Among different types of hormone replacement therapy (HRT), a transdermal formulation appeared safest in terms of venous thromboembolism (VTE) risk, according to researchers in England.

In a retrospective analysis of about 80,000 women who experienced VTE and some 390,000 non-VTE control women, 7.2% of VTE patients were exposed to HRT within 90 days of the index date compared with 5.5% controls, according to Yana Vinogradova, PhD, of the University of Nottingham, and colleagues.



But there was no added risk for VTE associated with HRT patches, gel, or subcutaneous formulas (adjusted odds ratio 0.93, 95% CI 0.87-1.01), they wrote in BMJ."

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