Slurred or confused speech is a Hypothyroid Symptom

#2
Me! I am now on thyroid meds and it has improved. Entirely gone away at some points. But I am still trying to optimize on my dosage.
 
Thread starter #3
Yes same here... I had it bad and then they got my thyroid sorted out and it all disappeared and I was great for 3-4 years. But now there is some other reason my T3 receptors are not working and I have those slurring/ mix words symptoms again. Not as bad as I was originally but just enough to know that it's back.
 
Thread starter #5
I have tried that and it makes no difference. My FT3 is at the very top of range taking 25mcg of Cytomel daily. Even if I take 100mcg daily nothing changes. The added amount you need during winter months (which may be because of less vit D) is only a nominal amount.
 
#6
Do you take Thyroxine also? Checked Ferritin recently? Adrenal issues in check? I would look at Reverse T3 also...though there is debate on whether RT3 actually has a tangible effect or not.
 
Thread starter #7
Yes I also take 200mcg of Synthroid. Ferritin is at 191. RT3 is fine according to Dr. Saya. I take hydrocortisone 3 times daily (15+10+5) because I'm hypothyroid. Dr. Saya says although my problem is akin to T3 pooling is not exactly the same... he says my T3 receptors are the issue and something is stopping those from working correctly. I need to go and see him because the lab tests he asked me to get I cannot get in Canada. So I think I need to fly to Florida and do whatever it takes for him to be able to Dx this problem.
 
Thread starter #9
You can't test T3 receptors as far as I know except for RT3. Because my RT3, ferritin and cortisol labs are good we assume it's another reason. He asked me to get a TBG and a full Iron Panel and sensitive E2. Where I live only Hematologists can Rx an Iron Panel and they don't do the the TBG or sensitive E2 labs here. Because a hematologist is a specialist who you get referred to, it can take 2 years to see one unless you are dying of cancer then you get fast-tracked. So I'm running out of steam trying to get to the bottom of all this. I had a very informative telephone appointment w/ Dr. Saya and he knows where to look but I'm unable to get those labs done. Time for me to get my butt to the USA and get some labs that Dr. Saya can work with.
 
#10
I would be more than interested to hear if you get things resolved...I have seen your stories before and I feel like we are in somewhat of a similar position.
 
#12
There was a poster here awhile back stating that due to non fluctuating test levels (since we are all on exogenous test, our levels remain constant with the time of day, unlike natural test that fluctuates and is higher in the mornings), it will eventually cause everyone on TRT to become hypothyroid.

He states he was part of a research trial or something along those lines.

I am unsure if this is the case, however it has me slightly worried.
 
Thread starter #13
Mountain man, yes exactly and nothing political about this either. That video of him slurring his words is exactly what this is like. Actually it's a perfect example. There are other symptoms that hypothyroid people have like a delayed response or not understanding fully until they've had time to think about it. Hypothyroid people are not quick on their feet and they do have a tendency of repeating themselves. Is that familiar?
 
#14
Mountain man, yes exactly and nothing political about this either. That video of him slurring his words is exactly what this is like. Actually it's a perfect example. There are other symptoms that hypothyroid people have like a delayed response or not understanding fully until they've had time to think about it. Hypothyroid people are not quick on their feet and they do have a tendency of repeating themselves. Is that familiar?
Yes. We know he hates exercise, believes it will wear him out, loves to eat fast food and junk food, and is overweight.These medical issues are only going to get worse without some lifestyle changes. Image being his doctor and having to tell him to lose weight, clean up his diet, and exercise?
 
#15
Wow I noticed this went away after starting Nature Throid (1.5 grain) and thought most of my life I had a speech problem. It was really on incredible. Though after being on for 6 months at 1.5 grain I do occasionally slur speech or get stumped on my words. Where I could almost articulate and read at hyper speed before. Anyone have this problem and did you have to adjust dose upwards after a long period of time? My T3/T4 levels looked good last time I checked....
 
#16
Are you only on Nature Throid? The T3/T4 ratio in pig thyroid does not match the ratio within humans since a normal, healthy thyroid produces somewhere in the range of 10:1 T4 to T3. It appears that over the long run, your T4 became depleted which is why your symptoms have returned. I would suggest you add more T4 to your regimen and see how you respond.

Another thing to note is that a lot of the thyroid dosage recommendations out there are targeted towards women since 90% of hypothyroid cases are female. Unfortunately as males, too much T3 can drive up our SHBG and inhibit our testosterone so that's something to be aware of. I would argue that males tend to do better on LESS T3 than women. My own experience fits this theory. I was on WP Thyroid 2 grains for 2 years, even adjusting to 3 grains since it was hammered in my head that fT3 should be within a certain range. I only started making real progress after dropping my WP Thyroid to 0.5 grains and upping my T4 to 100 mcg.

Lastly, T3 and T4 levels don't tell you everything. For example, T4->T3 conversion can happen intracellularly and that's something we can't test for yet (look up Type 2 deiodinase). Good luck!
 
Thread starter #17
Everyone is different. I don't buy the concept that men are different than women. I believe women are more attentive at staying on top of their healthcare than men are. I feel much better with higher T3 than lower. For you lower is better. I've tried that and it didn't work. Because you do better on lower amounts doesn't translate to all males needing less. All I'm saying is that cannot be said as a blanket statement. I believe there are more hypothyroid people than is reported. Only because hypothyroidism is still largely determined by the TSH test which we know doesn't define hypothyroidism. But it meets medical administration's budget for testing purposes.
 
#18
Thanks for the reply! Let me clarify a few things and see what you think. Originally the doctor noticed my T3 was on the low end and T4 looked fine (upper 3/4 of range). He said I possibly have an issue converting T4 into T3. Now that I’m on NTG 1.5 grain my T3 is in the upper range and T4 is stil upper but actually did not go up much. I’m thinking the T3 was the actual issue for me.
 
Thread starter #19
fitnessguy,
I had the same issue. My TSH was good (well below 2) and my FT4 was mid range but my FT3 was just below range. The hypothyroid symptoms that affected me most was fibromyalgia. I had read all of Dr. John Lowe's work re T3 and spoke with my MD and we agreed to try NDT. It worked great and was a huge improvement but I still had a little fibromyalgia. But I knew from reading all his research that I most likely needed more T3 and that would likely solve my fibromyalgia. So I took more and that brought my FT3 to just over range and sure enough the fibro was gone. The other benefit I noticed was that I had been living in a state of depression my whole life and upon getting my FT3 above range that disappeared as well. I found it increased my cognitive function and all the other silly hypo symptoms I had disappeared as well. Slurring of my words was now history.

I've read that some people that try their FT3 high get jittery and have to reduce their FT3. As usual everyone responds differently. After I stabilised on my new protocol I started having trouble with getting decent NDT so I ended up switching to synthetic T3 and having to add T4 to keep it balanced. This works well. When NDT worked well I found that I felt no different taking the synthetic's. Both made me feel great.
 
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