I am 29 yrs old, 210 pounds and just started TRT since levels were clinically deficient. My test was about 278 (300-1100) free: 5.8 (9-26) I am taking 120 mgs EW and HCG 2x a week for a month on, 2 months off. I have 2 mg of arimidex to take over the next few weeks. My doctor told me to take arimidex the morning after each shot. I have heard some horror stories about arimidex really messing with people and crashing their levels after use. I am concerned since my estrodial was extremely low. I believe it was like 6.8 (12-30 range or so) so I know what low estrogen feels like and how crappy it is. Instead of taking .5 mgs do you think I should start with .25 or wait until I feel high estrogen symptoms? what is anyone else's experience with this AI? Thanks.