Female Target Hormone Values - Getting Started with HRT/Thyroid

[blinblaugh]

Hey guys,

I've been on TRT and feel like its really made some changes in my life. Well, my wife (fit 39 yrs) noticing symptoms of her own is interested in looking into HRT/Thyroid for herself. She got a blood test and will be going in for her first visit. After looking at her results I am realizing I am clueless about female target values for Testosterone, Progesterone, Estrogen, and Thyroid (T3?). I know target values are largely individual but are their female targets that can give us a ball-park? I am looking for some insight to my wife's initial blood test prior to her first visit. I'll post the results below (caveat: I realize the panel she got doesn't include everything she needs).

Thanks!

Blinglaugh

CBC With Differential/Platelet
WBC 5.7 3.4-10.8 x10E3/uL
RBC 4.45 3.77-5.28 x10E6/uL
Hemoglobin 14.1 11.1-15.9 g/dL
Hematocrit 43.4 34.0-46.6 %
MCV 98 HIGH 79-97 fL
MCH 31.7 26.6-33.0 pg
MCHC 32.5 31.5-35.7 g/dL
RDW 13.8 12.3-15.4 %
Platelets 178 150-379 x10E3/uL
Neutrophils 57 Not Estab. %
Lymphs 34 Not Estab. %
Monocytes 8 Not Estab. %
Eos 1 Not Estab. %
Basos 0 Not Estab. %
Neutrophils (Absolute) 3.3 1.4-7.0 x10E3/uL
Lymphs (Absolute) 1.9 0.7-3.1 x10E3/uL
Monocytes(Absolute) 0.4 0.1-0.9 x10E3/uL
Eos (Absolute) 0.0 0.0-0.4 x10E3/uL
Baso (Absolute) 0.0 0.0-0.2 x10E3/uL
Immature Granulocytes 0 Not Estab. %
Immature Grans (Abs) 0.0 0.0-0.1 x10E3/uL
Comp. Metabolic Panel (14)
Glucose 84 65-99 mg/dL
BUN 29 HIGH 6-20 mg/dL
Creatinine 1.07 HIGH 0.57-1.00 mg/dL
eGFR If NonAfricn Am 66 >59 mL/min/1.73
eGFR If Africn Am 76 >59 mL/min/1.73
BUN/Creatinine Ratio 27 HIGH 9-23
Sodium 142 134-144 mmol/L
Potassium 4.0 3.5-5.2 mmol/L
Chloride 104 96-106 mmol/L
Carbon Dioxide, Total 25 20-29 mmol/L
Calcium 9.4 8.7-10.2 mg/dL
Protein, Total 7.1 6.0-8.5 g/dL
Albumin 4.5 3.5-5.5 g/dL
Globulin, Total 2.6 1.5-4.5 g/dL
A/G Ratio 1.7 1.2-2.2
Bilirubin, Total 0.6 0.0-1.2 mg/dL
Alkaline Phosphatase 58 39-117 IU/L
AST (SGOT) 29 0-40 IU/L
ALT (SGPT) 21 0-32 IU/L
Testosterone, Serum
Testosterone, Serum 9 8-48 ng/dL
Luteinizing Hormone(LH), S
LH 9.0 mIU/mL
Adult Female:
Follicular phase 2.4 - 12.6
Ovulation phase 14.0 - 95.6
Luteal phase 1.0 - 11.4
Postmenopausal 7.7 - 58.5
1 of 2
FSH, Serum
FSH 7.5 mIU/mL
Adult Female:
Follicular phase 3.5 - 12.5
Ovulation phase 4.7 - 21.5
Luteal phase 1.7 - 7.7
Postmenopausal 25.8 - 134.8
Estradiol
Estradiol 150.3 pg/mL
Adult Female:
Follicular phase 12.5 - 166.0
Ovulation phase 85.8 - 498.0
Luteal phase 43.8 - 211.0
Postmenopausal <6.0 - 54.7
Pregnancy
1st trimester 215.0 - >4300.0
Girls (1-10 years) 6.0 - 27.0

 

[Systemlord]

Your wife's testosterone clearly is a problem, I'm not sure the relevance of high LH, but if it was a guy I would say he is primary hypogonadal. I've picked up a few things on Dr. Saya posts and I can tell you dosing wise 20mg weekly would put most women in the supraphysiological range, 10-12mg split up multiple times a week is best for women. Most women in their 40's could use a little progesterone, by the time women hit 40 they just don't have the hormones they did in their 20's. Women hormones drop off a cliff long before a man's does.

It would be a good idea to run a thyroid panel checking Free T3, Free T4, Reverse T3 and antibodies.

There aren't many doctors who know how to treat women on testosterone, I can tell you Defy Medical does know how. Defy does telemedicine, all my medications are mailed to me. Consults are over the phone and labs are gone over and options for treatment are discussed.

 

[blinblaugh]

Sysetmlord,

Thanks for the reply!

I'll check out Defy Medical. The place I go to locally is pretty good and a decent price but if Defy can get us dialed in for a similar price maybe we can switch.

So her testosterone is obviously low. Question is how low... what is i mean by targets is the "optimal" target for the big 4 (test, est, prog, t3)? Is 40 ng/dL a good testosterone target?

Blingblaugh

 

[Systemlord]

Sysetmlord,

Thanks for the reply!

I'll check out Defy Medical. The place I go to locally is pretty good and a decent price but if Defy can get us dialed in for a similar price maybe we can switch.

So her testosterone is obviously low. Question is how low... what is i mean by targets is the "optimal" target for the big 4 (test, est, prog, t3)? Is 40 ng/dL a good testosterone target?

Blingblaugh

Your welcome,

High normal is usually targeted when SHBG is midrange or higher, lower SHBG and it's better to target mid range levels do to free testosterone being high when SHBG is lower. You might need to test SHBG before your wife goes on TRT, you need it to design a protocol. Of course if you go with Defy it's like a self driving car, doctor takes care of everything.

 

[blinblaugh]

Perfect, thanks.

What about for estrogen, & Prog? Shoot for high-normal or low-normal? T3 I am guessing we want high-normal?

 

[Systemlord]

Perfect, thanks.

What about for estrogen, & Prog? Shoot for high-normal or low-normal? T3 I am guessing we want high-normal?

At a minimum you want 40 to 50 pg/mL to prevent bone loss, but 60 pg/mL or higher is optimal, levels of about 100 pg/mL for younger women. Free T3 is better midrange or higher. Progesterone I don't know, progesterone is a precursor to the sex hormones estrogen and testosterone.

Females hormones are always changing, men's hormones are more stable. Now you know why...

 

[blinblaugh]

Thanks Systemlord. That helps use get a idea before we go in for our visit.