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Your Labs and protocol look good and should be conducive to good function. Have you had your DHT and Prolactin tested? When guys report good morning wood but poor function you have to suspect that the problem is more to do with neurotransmitters than with hormones. In your shoes I would ask...

My own dose of Clomid is ~8mg daily (1/6th of a standard 50mg tab). Mesterolone 75mg to 150mg daily - I like to keep levels in flux so vary the dose appropriately. If improved libido is your goal then give the mesterolone time to work; you maybe need a "reset" in which neurotransmitters are at...

A dose reduction might help. Your DHT would normally go down with a lower TT though the reduction would not necessarily be linear. Prolactin looks fine. My belief remains that you should discuss your DHT levels with your healthcare provider.

As a standalone number 700 is decent and many guys would have good function at that level of DHT. However with continued libido and erection issues you would potentially find improvement by getting the level up to ~10% of your TT; 1,100 (110 ng/dl).

Normal conversion is around 10% of TT which for you would indicate DHT ~110ng/dl, probably a bit above top of your Lab's range. How you function, as ever, is more important than the absolute number and serum DHT provides a "hint" of activity in tissue. If the level appears low you can increase...

I would suggest to include DHT in your next Labs. The fact that you were feeling good on the T Cream, until absorbency became an issue, and are now having issues on the injectable (at your good levels of FT & E2), might be due to too low 5a-r conversion to DHT. Typically DHT levels are...

It's difficult to decipher your Labs and what your current levels of TT and E2 are but if they're adequate then you should get your DHT and Prolactin tested. Low DHT or elevated Prolactin can adversely affect sexual function. You mention that T Gel is available to you; it's worth discussing...

Interesting results on your "CTD" experiments! Hope you're feeling well on it - you don't say too much about subjective results, though I assume adding the AI means you had symptoms from the large rise in E2. It will be interesting to see how you do with your plan to halve the dose to 1 Click...

DHT - your TT is ~1,100 so if you were converting to DHT @ 10% (the average for healthy eugonadal males) your DHT "should" be around 110. Most Lab ranges top at 85-90 so that would put you above range; your other hormones are above range so why not DHT? Yes, even if your serum DHT isn't low I...

Almost unbelievable that you could be on TRT ~18 months, with high levels of hormones, but not getting where you need to be, and now your doctor might order these tests - Prolactin, DHT, Thyroids - like they're some sort of curiosity. Look at the DiscountedLabs ED Bloods Panel - all these are...

Your estradiol is undoubtably high, however Before resorting to an AI, particularily where no "sensitive" testing is available, I would look at raising androgens (FT & DHT) to balance hormones. While always keeping up the good work in minimising body fat. As you're in Europe, have you tried...

It seems that it's often a combination of high levels of E2 and the cumulative effect of the longer half-life of the ZUC isomer that is the undoing of a Clomid protocol. If it leaves you essentially estrogen dominant, in brain and balls, then the potential good effect of the stimulation, with...

I don't know too much about Bodybuilding per se, but my belief is that the answer to the OP's underlying question is that, at physiological levels of TT we need the 2 metabolites (DHT and E2) to be in balance, and that as TT is increased to supra-physiological levels that balance will eventually...

Your 1st and 2nd Test results were quite consistent and showed good levels of the sex hormones; decent TT (~2% FT) and E2. The 3rd Test, at another new Lab, does show LH suddenly High, that could be an anomaly, which you won't really be able to confirm at your Labs tomorrow as you'll be...

Have you ever had, or considered, any counselling to address these issues? Forum member @Mountain Man has some great recent posts where he explains how, in particular, CBT can help guys.

Normally when making changes to a protocol it's best to make one change at a time in order to evaluate what's helping/hurting. As the disproportionate rise in E2 happened when your only apparent change, between the two Labs, was an increase in the injectable T then the decrease to 105mg would...

The situation of good all round health markers and high TT that is confounded by too high SHBG is one that faces a lot of (mostly) younger guys. I note that you're in Europe and have started on a course of Proviron. Hopefully that will work well for you both in terms of increasing libido and...

Don't get too caught up in the whole "sensitive" E2 testing issue. You have what's available to you - immunoassay - snd that's more than good enough (I've had ~30 tests in London over the last 20 years and have found the E2 results to be both consistent and instructive). My strong advice, as...

You're correct but please don't whisper it; shout it from the rooftops! The original introduction of the long esters of T had nothing to do with efficacy - successfully treating the symptoms of hypogonadism - and everything to do with Doctors' wish to ensure patient compliance with the...

I would suggest that you enquire with your Doctor what is being done to monitor your androgen levels, particularly DHT. At that dosage of TCyp, if your FT and E2 levels are top of Lab range, or above, and your low mood and libido symptoms persist then check first DHT and then Prolactin. If...

That's the answer! The OP raises an interesting point about caffeine/aromatase and such concepts are worthy of investigation. However, much like DIM and CDC, the effects amount to little more than rearranging the deckchairs for guys that over aromatise and under-convert (via 5a-r) to DHT on the...

In your shoes I would look to a change in healthcare provider and further I would consult with Dr Saya and his team at Defy medical. Your Urologist made a good call in trying Clomid. You had a robust response - a doubling of TT - and temporary relief of symptoms. It's possible that you would...

As part of that it would be interesting to see an overview of the potential efficacy of T Cream monotherapy (applied to scrotum and/or other sites) compared to T Cream use adjuctive to injectable T. Also the desirability of clinics/healthcare providers ordering DHT serum as part of the Lab draw...

Looking at your (six month old) Labs I would say that, although you had good levels of TT and FT, your Prolactin was too high and your DHT was too low. Both of which would negatively impact your sexual function. It could be your Prolactin was temporarily spiked (eg if measured some hours after...

I would suggest that you get DHT measured at your next blood work. Your Doctor's comment that he's only interested in your TT and E2 levels essentially means that unless you have at least average 5a-r conversion to DHT then you'll always be reliant upon an AI to balance your hormones. That might...

I believe that your suggesting a number for DHT - 10% (or above) of TT - will be helpful to the many guys struggling to acheive relief of symptoms whilst on TRT. We know 10% is the broad average for healthy eugonadal men. There are a number of posts here on the Forum from (often younger) guys...

Be careful of adding anything to a Serm (Clomid or otherwise) that is potentially suppressive of the HPTA. DHEA, for example, can convert to (edit) estrogens and the resultant suppression could counteract the stimulation from the Serm. Proviron as pure methylated DHT cannot convert to E2. As...

I used mesterolone (DHT analog) alongside Clomid long term and those 2 pharmaceuticals used as an adjunctive therapy worked well for me. Usually marketed as Priviron it's not licenced in some countries - including USA. It lowers SHBG as binds to the receptor with greater (~4x) affinity. The...

Entirely possible as changes in levels of the sex hormones can bring those side effects - look at teenagers. Surely better though to feel great than worry about that possibility? Effects probably transitory anyway and can be dealt with as necessary. Oily skin would likely accompany an increase...

My take on your Labs, and the symptoms you report, is that your DHT is too low. Your other numbers do indeed potentially look "good" but your inadequate 5a-r conversion to DHT prevents you from getting the results that you seek. You didn't include your lab ranges but, assuming typical ranges...

That's interesting that you're talking about the T:E2 ratio in your clinic as we've been discussing it again in the last few days here on Excelmale so your findings would add greatly to the discussion. I note that T:E2 is used elsewhere in the diagnosis and management of various morbidities...