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Random question, but… Hypothetically, assume an individual injecting 100mg once per week. Supposing that the injection site is the same (VG), would two 50mg injections at the same time (one on each side) be the same as one 100mg injection? Curious if the larger oil depot with the single...

How long does it take SHBG to change if, for example, it has been lowered through the use of say high dose testosterone or the use of oxandrolone? If one were to lower the dose of testosterone or cease using oxandrolone, when could one expect to see a rise in SHBG in lab work? We’ll assume...

I’ve read that using exogenous testosterone, and in particular having high TT/FT levels, can cause some “stiffening” of tendons. I’m experiencing extremely painful, chronic tennis elbow. It didn’t occur in isolation - it is an overuse injury. But one that simply will not heal. It’s not as if...

Assuming TT/FT levels are roughly equal in both cases, would there be any difference between cream and injections in terms of body composition/muscle building?

Been a while since I’ve gotten this product from them. Last time they were capsules. Just received some and they’re little round light green tablets with a split mark in the middle. That sound right? I can call in the morning but had planned on taking one tonight.

I know of at least one member (Gman86) here who has tried it. Anyone else doing it/tried it and care to share your experiences?

I'm curious to know whether or not long-term HPTA shutdown, or some other mechanism from long-term TRT, has any effect on brain serotonin levels, serotonin transmitters, or the brain's ability to uptake serotonin. Anyone have any insight here? @Mountain Man ?

What is the half life of nandrolone decanoate? Some sources say 6 days, others say 6 to 12 days... Trying to figure out when, if one were to inject say 40mg today, the ND would no longer be active/in one’s system.

I've been at this for a few years now. I've tried various methods of administration and protocols, but always seem to settle back to what has been my go to protocol of 60mg E3.5D cyp. After experimenting with a few different protocols over the past year - daily prop, daily cyp, EOD cyp, cream...

I recently came across a thread where someone (@Cataceous ?) posted a nice chart showing many different compounds, family, propensity to aromatize to E2. Can’t find it now. If anyone could find it based on my vague description, I’d appreciate it!

I created the plots below using a tool from another site, which I'm sure many of you have seen before. I'd like some clarification as to whether or not the way I'm interpreting the data is correct. I'm aware of the ester weight/percentage for the two esters being compared, and that 120mg cyp...

What effects, if any, does TRT have on neurotransmitters, particularly on serotonin? I know that in the initial stages of TRT, there is a pronounced effect on dopamine - I have been told that this is what causes the "honeymoon" that many guys experience. Are there neurotransmitter imbalances...

I'm struggling with how to articulate my question, but here goes: My DHT levels are relatively low, even with higher levels of TT/FT. Having used scrotal cream and boosted DHT levels in the past, I do feel like I benefit from it. If I supplement my protocol with scrotal cream to increase DHT...

I recently had lab work and got the ECLIA E2 test. I know my results for both tests are "high", however I'm curious as to how any comparison might be made to previous tests that used LC/MS/MS. Previous E2 labs using LC/MS/MS: 47.2 pg/ml (8.0-35.0) Current E2 labs using ECLIA: 69.2 pg/ml...

Is there any kind of relationship with injection frequency and DHT levels? For example, I have found that spreading out injections lowers my HCT levels. Others find that it lowers E2. I'm having a hard time imagining that injection frequency could affect DHT levels and would think that it would...

I’m not as familiar with the science as some on this site, so forgive me if I don’t know the correct terms for what Im trying to describe. Ive heard/read something along the lines of “nandrolone has a greater binding affinity...this in turn leaves more T unbound and results in higher FT...this...

Having tried many different protocols, I felt like I had to give dailies a try. My approach to this is that I plan to do this for life so might as well try it all and see what works best for me. I’ve spent enough time here reading about how dailies do/do not work for people so was prepared to be...

This article may be of interest to some forum members: U.S. court let Merck hide secrets about popular drug's risks

Does anyone that has used Empowers's cream happen to have a totally empty Topi-Click container sitting around? I'd really like to know how much a clean and empty container weighs, in grams if your scale will do that but any unit would be great. Thanks!

Curious to hear from guys that have been on cream long-term. Have you been stable on a cream protocol for a long time, and if so, have you had to make minor adjustments along the way or change application sites?

I've heard of guys switching from big pharma to compounded (injectable test cyp, etc) because they stated they had a reaction to cottonseed oil, etc. But has anyone gone the other way - from compounded to big pharma - and noticed a difference, for better or worse?

After all the talk about scrotal cream, I just had to try it for myself. I had used cream before, but not exclusively on the scrotum and only once per day. This time around, I tried 100mg AM and 50mg PM, applied all to scrotum. I took one set of labs before my morning application, about 12...

For guys that are using 2x/day cream: - What dose do you take in the AM? PM dose? - What time do you apply PM dose - right before bed? - Had you previously tried 1x/day and found you got better results with 2x/day? I guess I’d also be interested in hearing from anyone who switched from 2x/day...

A bit of a hypothetical question here, but something I've been curious about. Supposing someone with relatively normal SHBG (mid 20s-mid 30s) is on a T. Cyp. E3.5D injection protocol and has slightly elevated E2 and HCT. TT/FT slightly above range at trough. For this example, let's say they use...

Have any of you tried both MWF and EOD injection protocols and noticed much of a difference, either subjectively or in your lab results? I'm looking to go either 40mg MWF or 34mg EOD. Same total weekly dose in either case. MWF seems easier and I find myself doubting that the extra 6mgs...

Suppose a guy has slightly elevated hemoglobin and hematocrit. As a result, a protocol change is made to an overall lower weekly dose and smaller, more frequent injections. No blood donation or therapeutic phlebotomy. Assuming the protocol change would positively affect HGB/HCT, how long would...

I know I've seen information on this here before, but I haven't been able to find it with a search. Assuming you have 200mg/ml Testosterone Cypionate, how do you calculate how much actual testosterone is in the solution (less ester, benzyl benzoate, benzyl alcohol, etc)? For example, if a guy...

Many of us on TRT are on it precisely because we are interested in managing our overall health and fitness. Many guys who are interested in fitness also commonly use whey protein shakes as a post-workout supplement. If you're struggling with acne, it may not be the TRT that is causing it. Try...

For those of you that inject daily: do you preload your syringes? If so, how far out do you preload - a few days worth? A weeks worth?

For those of you who have tried both EOD and ED injections, was there any significant difference, either in how you felt or in your lab results? I ask because it appears that assuming the same weekly dose, average levels on ED and EOD would be exactly the same (using cypionate).

For more than a year now I've been using 28g 1/2" needles. Recently, I've been using 30g 1/2" needles and like the smaller gauge, mainly because I rarely get any leakage of oil from the injection site when using them. Lately, I've thought about going to 30g 5/16" needles. I inject SubQ in the...