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    What is considered optimal Estradiol, Ultrasensitive range?

    I think the other day I may have taken too much AI and crashed my E2 cuz had numb cock and no libido and Viagra had almost no effect. 2 days later I took Estradiol blood test and Estradiol Ultrasensitive LC/MS blood test. The results… Estradiol = 21 (Range: < OR = 39) Estradiol Ultrasensitive...
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    I Haven’t Slept in 4 years. What to Do?

    I recently noticed that I get better sleep if I use anastrozole. Although I am not 100% sure my improved sleep is from lowering estrogen. But I will keep experimenting with it. I’ve always avoided using AI in the past. This week I have managed to get about 6.5 to 7.5 hours of good sleep per...
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    I Haven’t Slept in 4 years. What to Do?

    Thanks. Good info. I think I will be trying several things from the list you gave. I really like the idea of time release capsules. I wonder what time release capsules last the longest. I was just reading one that said it last 2 hours.
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    Body Acne -- Caused by DHT or E2?

    The Bathery Exfoliating Bath Cloth and Walgreens Acne Treatment Cleansing Bar - With 10 Percernt Benzoyl Peroxide work amazing for me. I am very prone to acne. Been on accutane when i was a teenager. When I started TRT I would get bad acne from just 120mg per week. Now I can use 160mg and not...
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    I Haven’t Slept in 4 years. What to Do?

    I mean, I haven’t slept in 4 years without taking drugs. I’ve been on TRT for 4 years and I think that is why I cannot sleep well. When I started taking TRT I can only get about 4 hours of sleep. Then I wake up and I am wide-awake, but also tired. I cannot fall back asleep unless I eat a high...
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    Eye spy a STYE

    I had this same problem when I was NOT on TRT. I get an internal stye on one eye, then another in a different eye. It just keep repeating. The problem is you have some type of disfunction with the glands. Maybe from medication, could be excessive strain on eyes from computer, hormonal imbalance...
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    Im a COVID ICU nurse. Ask me (almost) anything.

    I’ve read that if you’ve recently been sick with one of the common coronaviruses that have been circulating for years then one might have some level of immunity to SARS-2. Any solid evidence regarding this? Cuz if that’s the case maybe we just infect ourselves with the common cold/coronavirus...
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    President Trump is taking one tab of hydroxychloroquine and zinc per day.

    I am sure he and most important WH staff already had the Covid-19 vaccine shot a long time ago. They just can’t tell people cuz it wouldn’t look good. Even Fauci said you could create a vaccine tomorrow but you’ve got to test to make sure it’s safe and effective for the masses.
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    Insomnia help. I have been on TRT for 15 days and can barely sleep.

    I ran out before writing that post. Zero side effects. But sleep is bad again.
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    Insomnia help. I have been on TRT for 15 days and can barely sleep.

    Been on TRT 3 years and that's when sleep stopped for me. I’ve tried melatonin, sleep aids, Ambien but the half-life of all of that is too short. And Ambien does not relax the mind, it speeds it up. And people here say Ambien causes cancer. I have tried Restoril (temazepam) and Xanax. 15mg of...
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    Why the Coronavirus Seems to Hit Men Harder Than Women...Estrogen Levels?

    When I was much younger I would use 200mg of testosterone per week for bodybuilding. That’s all I needed to build a lot of muscle since I have very low SHBG. But long-term at that dosage it caused an immune disorder. My immune system started attacking some of my organs. This was confirmed by an...
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    Coronavirus COVID-19 Update: Hydroxychloroquine and Other Treatments

    So how can we get the meds? Empower got it? Can we get telescript? Who got the connection?
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    Are TRT Patients More Vulnerable to COVID-19?

    Well someone had to ask. Seems like woman do better in survival rate. I read that testosterone has an immunosuppressive effect while estrogen has an immunoenhancing effect on the immune system. Estrogen has been shown to regulate immune response. This enhanced immune reactivity in females...
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    SHBG level inversely related to insulin level

    Yes I am pretty sure I have some level of insulin resistance and I am sure it is making it worse. I am gonna lower T3 dosage.
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    SHBG level inversely related to insulin level

    Erections were good despite me having E2 of 46. But when or if I use anastrozole to control estrogen erections dramatically improve. But it doesn't improve sex drive. Sex drive ain't like it was when I was 16.
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    SHBG level inversely related to insulin level

    I’ve read people with low SHBG have more sever acne. Not sure if that is true. But I am very prone to acne even at 70mg of Testosterone per week. That’s the only reason I wanted to raise my SHBG. I thought it would lessen my acne. Now my goal is to leave my SHBG alone and treat my acne. I’ve...
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    SHBG level inversely related to insulin level

    I took metformin and it didn’t increase SHBG. I took metformin and T3 together and it didn’t raise SHBG. I took anastrozole and it didn’t raise SHBG at all. In fact it went from 9 to 8.
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    Low cortisol levels (adrenal exhaustion) vs. low calories and starvation mode

    What's your body temperature morning noon and night? Anyway. I know an endocrinologist who specializes in weight loss. He starts his clients eating low carb and low calorie. Then he lowers calories more after 6 weeks because the metabolism slows. Eventually the metabolism slows so much that he...
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    What is reliable way to measure T3 dose?

    How do I measure what the correct dosage of T3 is right for me? Should I slowly increase my dose until my RT3 goes to normal level? Should it be based on TSH? Should it be based on body temperature and pulse rate (I am aware that my resting pulse shouldn't exceed 80 and body temperature 98.6)...
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    What is Optimal Estradiol Range for Libido/Erection

    Didn’t know this thread was still going but as an update I take about 0.65 of Arimidex per week. I crush the pill into a powder and divide that little bit into 7 equal-ish parts and put it in vitamin container. Each day I take that little bit. That’s probably overkill but erections are 100%...
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    Thinking about taking my life because of ED!

    I started seeing a cardiologist because I started getting benign heart palpitations, which is the most common heart condition worldwide. It often comes with age or maybe past steroid use or because of metabolic disorders like insulin resistance. I have no blood flow problems. Been scanned by...
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    Thinking about taking my life because of ED!

    I remember having the best erections in the world. Steroid abuse changed that permanently. My erections died while on long-term (many years) steroids. Went on a first date with my now second wife and dick didn’t work…but Viagra did. So I got off all hormones, even got my wife pregnant 3.5...
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    Elevated PSA at 32 years old, Should I stop?

    When I was between 32 and 34 years of age my PSA went from 1.9 to 1.2 to 1.4 to 1.7 then to 5.6 My Urologist knew I had a history of steroids so he did a biopsy. Turned out to be nothing. He put me on high-dose of antibiotics and my PSA went back down to 1.0 where it has remained for 12 years...
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    Low-carb/low calorie diet Vs. low calorie dense, low fat foods?

    So far my experience with low carb/low calorie dieting (keto) is that it SEVERELY slows down your metabolism. Granted I’ve lost about 20 lbs but I am sure half of what I lost has been muscle. Currently I consume 1500 to 1600 calories per day. Go to the gym 6 days per week (for 26 years). Walk...
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    Treating high RT3 with T3. How much is too much?

    I’m not sure if anyone knows the true role of RT3. It’s said that a low carb/low calorie diet (starvation diet) will elevate RT3. When RT3 is high the metabolism slows down. Internet articles suggest that RT3 blocks T3 thyroid receptors and thus prevents T3 from speeding up the metabolism. So...
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    Treating high RT3 with T3. How much is too much?

    Good to hear stories like yours. I have mind fog, RT30 and also gain weight just looking at food. I feel like doctors under dose me when I take Cytomel. Thanks for sharing.
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    Treating high RT3 with T3. How much is too much?

    Thanks for the info. Did you feel like your metabolism increased? Were you trying to lose weight or just doing it to feel better? If you were doing it to lose weight did you experience weight loss?
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    Treating high RT3 with T3. How much is too much?

    I noticed that actual endocrinologists who treat patients for elevated RT3 using Cytomel often prescribe T3 dosages between 10 to 15 mcg per day. Then I see other people who say they get 50+ mcg prescribed. How do you determine what dose to use? Is there a danger taking 25 or 40 mcg?
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    Thyroid blood results while on low carb. Are my results normal?

    But how many calories are you consuming per day? These online weight loss calculators or apps are inaccurate. I just did one now. It said I should consume 2,638 calories per day to lose 20 lbs. in 90 days. That’s doing hard exercise 6-7 days/wk. It said my maintenance calories should be 3,406...
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    E2 sweet spot, it's a ratio

    Maybe after trying this I will try your method. But this is just a short-term experiment. I’ve never focused on micro-managing my TRT. I inject every other day, take a couple OTC vitamins and that’s it. Otherwise I don’t take HCG, DHEA AI etc. And from what I’ve heard AI shouldn’t be a long-term...
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    E2 sweet spot, it's a ratio

    I keep hearing people say that when E2 is out of range it can cause softer erections, affect SHBG or increase/decrease acne, libido and other effects. I have low SHBG (9), high E2 (46) and my FT is usually 19 or 20. My total T is usually between 436 and 460. I inject 70 mg per week, small...
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