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Hope you understand the PKs! 2 different animals here oral TU vs injectable esterified TC/TE. Oral TU is dosed 2x daily which results in 2 daily peaks/troughs 24/7. Again the starting dose is 200 mg twice-daily. If you do not achieve high enough levels then your dose will need to be...

What is your dose? Did you test peak or trough? Common starting dose is 200 mg twice daily (dose spread 12 hrs apart). Keep in mind some men may not achieve high-enough peaks on the standard dose and will need 300 mg twice daily or in some cases 400 mg twice daily...

Not a chance! Most healthy young males would be hitting a cFTV 13-15 ng/dL and this is at peak (short-lived). With a very high TT 970 ng/dL, high SHBG 53 nmol/L and Albumin 4.3 g/dL (default) your FT 17.2 ng/dL would be healthy and far from lowish/low. Even then the shitkicker here is if this...

@Mountain Man No one should be using/relying upon the known to be inaccurate direct analog immunoassays especially in cases of altered SHBG. Again when it comes to testing free testosterone you would need to use/rely upon the most accurate assays such as the gold standard Equilibrium Dialysis...

@Mountain Man Had to be more thorough here! Your FT was tested using the known to be inaccurate direct analogue radioimmunoassay (RIA) reference range Male: 20-50 years 0.87-5.47 ng/dL. Never seen this reference range for FT as most are using/relying upon Labcorp direct analog enzyme...

https://www.excelmale.com/threads/medherant-transdermal-patch-development-collaboration-with-bayer.30261/ https://www.excelmale.com/threads/preliminary-results-of-clinical-study-of-medherant%E2%80%99s-testosterone-patch-for-post-menopausal-women.30260/

https://www.excelmale.com/threads/first-testosterone-patch-for-menopausal-women.27355/#post-257240

https://www.excelmale.com/threads/first-testosterone-patch-for-menopausal-women.27355/#post-257240

https://www.medherant.co.uk/news/medherant-transdermal-patch-development-collaboration-bayer Coventry, UK (25 March 2024): Medherant Limited (“Medherant”) announces that it has entered into a Development Collaboration Agreement with Bayer for the development of a transdermal patch product for...

https://www.medherant.co.uk/news/preliminary-results-clinical-study-medherant%E2%80%99s-testosterone-patch-post-menopausal-women 10 April 2024 (Coventry, UK). Medherant is pleased to announce the preliminary results of the Phase I study of its testosterone patch technology being conducted at...

https://www.excelmale.com/threads/androgen-levels-in-women-across-the-menstrual-cycle.26426/ Key point here! *The present study aimed to examine the changes in the T and DHT levels across the menstrual cycle in carefully characterized healthy young women using LC-MS/MS assays certified by the...

post #14 https://www.excelmale.com/threads/testosterone-for-women.30026/

Dr. Harper and I discuss the importance of testosterone for women’s health, including muscle mass, metabolism, mental health, and the health of the genitourinary tract. We address common questions and misconceptions about testosterone, such as why it isn’t easy to prescribe and the normal ranges...

https://www.excelmale.com/threads/t-cyp-100-mg-week-night-sweats-anxiety.28530/page-2#post-265733 Regarding those struggling with high hematocrit here is my reply from another thread: As you can see your RBCs/hemoglobin/hematocrit is elevated which is a common side-effect when using exogenous...

You must have meant 11.6 ng/dL as there is no way your FT is 1.16 ng/dL with a top-end TT. If your TT is at the top-end of the reference range even with highish/high let alone absurdly high SHBG your FT would not be that low! What method (direct immunoassay, ED, UF, calculated) was used to...

Even then we need to wait on harmonized FT reference ranges based on a standardized FT assay (ED-LC/MS/MS). Similar to what was done for harmonized TT. *Assays that are standardized are designed to provide accurate results, traceable to “true” value-assigned certified reference materials and...

post #9/11 https://www.excelmale.com/threads/controlling-the-polycythemia-effect-associated-with-trt.29985/#post-276924

Key Takeaways *Testosterone has a dose-dependent stimulating effect on erythropoiesis *Erythrocytosis is the most common dose-limiting effect of testosterone therapy *The mechanism by which testosterone increases the Hct/Hb is not clear but may involve changes in the levels of hepcidin...

https://www.thebloodproject.com/cases-archive/testosterone-therapy-and-erythrocytosis-2/ Introduction Androgens play a crucial role in the development and maintenance of: Male reproductive and sexual functions Body composition Erythropoiesis Muscle and bone health Cognitive function...

https://www.excelmale.com/threads/management-of-luts-attributed-to-bph.28584/ https://www.excelmale.com/threads/pissed-off-urination-gone-wrong.28114/ https://www.excelmale.com/threads/aquablation-powerful-relief-for-big-prostate-luts-in-bph.28060/...

In the final edition of EAUTV at EAU24 our expert panel discusses Male LUTS. Moderator Prof. Jean-Nicolas Cornu and discussants Prof. Marcus Drake and Prof. Thomas Herrmann cover the distinctions between prostate symptoms and LUTS, storing and voiding issues, and more.

https://www.excelmale.com/threads/manitobas-first-mens-health-clinic.24847/

https://www.excelmale.com/threads/uncovering-the-truth-about-low-testosterone-and-trt.30255/

Timeline for Improvement *Patients often wonder how soon they can expect improvements in the signs and symptoms of low testosterone after starting TRT. Typically, blood testosterone levels increase before noticeable symptom improvements occur. In general, most patients begin experiencing...

https://www.excelmale.com/threads/enobosarm-and-glp-1-receptor-agonist-combination-to-treat-muscle-loss-associated-with-weight-loss-drugs.30254/

https://www.excelmale.com/threads/enobosarm-and-glp-1-receptor-agonist-combination-to-treat-muscle-loss-associated-with-weight-loss-drugs.30254/

https://www.excelmale.com/threads/enobosarm-and-glp-1-receptor-agonist-combination-to-treat-muscle-loss-associated-with-weight-loss-drugs.30254/