18 Year-Old With Testicular Atrophy

[Lobo00]

Leydig cell desensitization is not an issue at normal doses. Setting aside aromatization, my guess is you should be looking for the dose that maximizes testosterone production. This undoubtedly varies among individuals, but according to one hCG modeling paper, with EOD dosing the peak is likely to occur in the range of 250 to 1,000 IU. Ideally you would start on the lower side, like 300-400 IU EOD, and work up slowly, measuring testosterone to ensure production doesn't decrease. Things may be a little confusing in the beginning because you will have an additive effect with LH until it's suppressed.

Okay, thanks, I have a few last questions.
1) Do you think it is better dosage EOD or ED? for example would be better 400IU EOD or 200IU ED?
2) After how many days would I see my testicles increase their size? How many weeks should I take HCG? 8-12 weeks?
3) Post HCG I have to use Nolvadex (I read about 10mg ED or EOD) to recover my own LH and FSH right?
Thank you sir

 

[Cataceous]

Okay, thanks, I have a few last questions.
1) Do you think it is better dosage EOD or ED? for example would be better 400IU EOD or 200IU ED?
2) After how many days would I see my testicles increase their size? How many weeks should I take HCG? 8-12 weeks?
3) Post HCG I have to use Nolvadex (I read about 10mg ED or EOD) to recover my own LH and FSH right?
Thank you sir

1) I've seen both sides argued in the debate over whether ED or EOD dosing is better. For example, Dr. Crisler felt ED is better because it might better mimic natural LH production. However, the half life of hCG is about 36 hours versus maybe 20 minutes for LH. So it's questionable that serum concentrations of hCG can ever look like those of LH, regardless of dosing schedule. On the other side, Nelson has mentioned the possibility that peak levels of hCG are important. If this is the case then less frequent, higher doses may preferred. I would like to know if there's a reference supporting the idea.

Personally, I have tried both ED and EOD hCG dosing and didn't notice any subjective differences. But I didn't try ED for more than a couple weeks.

2) I would try hCG for at least one to two months. Many guys have seen improvements in this kind of time frame.

3) You do not have to use a SERM when stopping hCG. But these drugs can speed up the process of restarting the HP part of the HPTA.

 

[Lobo00]

1) I've seen both sides argued in the debate over whether ED or EOD dosing is better. For example, Dr. Crisler felt ED is better because it might better mimic natural LH production. However, the half life of hCG is about 36 hours versus maybe 20 minutes for LH. So it's questionable that serum concentrations of hCG can ever look like those of LH, regardless of dosing schedule. On the other side, Nelson has mentioned the possibility that peak levels of hCG are important. If this is the case then less frequent, higher doses may preferred. I would like to know if there's a reference supporting the idea.

Personally, I have tried both ED and EOD hCG dosing and didn't notice any subjective differences. But I didn't try ED for more than a couple weeks.

2) I would try hCG for at least one to two months. Many guys have seen improvements in this kind of time frame.

3) You do not have to use a SERM when stopping hCG. But these drugs can speed up the process of restarting the HP part of the HPTA.

I hope that HCG way can restore my testicles, I am only 18 years old and I am very worried about having done irreversible harm....
Even if my LH is 5.0 and my T is 6.0 ng/ml, it seems to me to be quite average values, I don't understand why my testicles have not recovered their size as well as LH and TT have recovered..