Citrulline was named for citrulline, or watermelon. It is converted by the kidneys to L-arginine and NO, or Nitric Oxide. Nitric Oxide is essential for the health of the artery. It feeds the inner lining of the artery, the intima. Diabetes, periodontal disease and other causes of arterial inflammation, or CV inflammation.
Pics show the intima layer and deposition of plaque, also immune system inflammation of plaque. Therefore, NO is critical to arterial health. Anything that improves NO can have a huge impact on health. Citrulline is therefore used for many things: erectile dysfunction, bodybuilding, cycling and other athletics, high blood pressure or hypertension, and even diabetes. The molecule is similar to urea and a part of the urea cycle.
The urea cycle fills several functions biologically. One of the most important is excretion of ammonia.
About Dr. Brewer – Ford Brewer is a physician that started as an Emergency Doctor. After seeing too many patients coming in dead from early heart attacks, he went to Johns Hopkins to learn Preventive Medicine. He went on the run the post-graduate training program (residency) in Preventive Medicine at Hopkins.
From there, he made a career of practicing and managing preventive medicine and primary care clinics. His later role in this area was Chief Medical Officer for Premise, which has over 500 primary care/ prevention clinics. He was also the Chief Medical Officer for MDLIVE, the second largest telemedicine company.
More recently, he founded PrevMed, a heart attack, stroke, and diabetes prevention clinic. At PrevMed, we focus on heart attack and stroke and Type 2 diabetes prevention by reducing or eliminating risk through attentive care and state-of-the-art genetic testing, imaging, labs and telemedicine options. We serve patients who have already experienced an event as well as those have not developed a diagnosis or event.
Our team of senior clinicians includes internationally recognized leaders in the research and treatment of cardiovascular disease, preventive medicine, and wellness.
We also provide preventive medicine by telemedicine technology to over 30 states. Contact Dr. Brewer at