Low E2 but high SHBG?

lookingforhelp · Aug 24, 2016

Quick question guys,

I've read a lot regarding high E2 causing high SHBG but I seem to have low E2 and raised SHBG?

my e2 was 8 (22-30) and my SHBG sits around the 40-50 mark. I am 26 and lean. Also having issues with fluctuating prolactin levels. I read a study somewhere regarding prolactin lowering Shbg. Will have to find it.

Am I a rare case? Can anyone help?

Thanks!

CoastWatcher · Aug 24, 2016

Remind us, are you on a TRT protocol at this point? Do you have other lab results?

lookingforhelp · Aug 24, 2016

Thanks for your quick reply coastwatcher. I haven't started TRT yet as I was waiting to complete a growth hormone stimulation test my endo had ordered for me to have. I have yet to receive the results as I only had it last week.

I am trying to really exhaust all possibilities before starting TRT but I am feeling worse and worse fast. Joint pain is terrible and I am in the beginning stage of developing arthritis in my hands... this is amongst all my other symptoms.

I have a lot of lab results but I am away from home currently and my computer with them saved on is there. When I get home I am going to upload them all to see what you all make of it.

I was just trying to understand SHBG by researching and I find a lot about E2 raising SHBG but nothing about other reasons for it being elevated.

ERO · Aug 24, 2016

It can be genetic as well, just as some cases of low SHBG. Not saying that is necessarily the case for you, just something to keep in mind.

Take a look at this list of potential causes: http://www.peaktestosterone.com/High_SHBG.aspx

Low E2 but high SHBG?

lookingforhelp

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