Injecting at night vs day

I know everyone has their own preference on what time of the day but I was thinking...

If a male's body naturally produces testosterone during sleep, wouldn't it make sense to inject at bedtime to mimic the body's own natural state? I inject around lunch time 3times a week subq.

Any comments, thoughts?

If you inject T every 3 1/2 days (or more), your levels stay nice and even = less problems

Yeah but I like to split my doses into 3 times a week. At one point I was doing daily, then went to EOD and now 3x per week. If there's a benefit to going back to daily (night time) I might try that out . Thanks for your input 😊

How much testosterone are you injecting? Are you working to control estradiol, is that why you have made the frequency changes?

i inject sunday morning and wednesday evening and I dont notice any difference between night and day

fmalianos said:

Yeah but I like to split my doses into 3 times a week. At one point I was doing daily, then went to EOD and now 3x per week. If there's a benefit to going back to daily (night time) I might try that out . Thanks for your input 

Click to expand...

no benefit, to daily injecting compared to three days a week

Vince said:

no benefit, to daily injecting compared to three days a week

Click to expand...

I've read this many times, but when my E2 ran wild this past summer, I went from twice-weekly dosing to three-day-a-week doing. Estradiol dropped a bit, when I went to daily dosing in an effort to avoid an AI, my E2 slid right down into range. I was surprised, but pleased.

CoastWatcher said:

I've read this many times, but when my E2 ran wild this past summer, I went from twice-weekly dosing to three-day-a-week doing. Estradiol dropped a bit, when I went to daily dosing in an effort to avoid an AI, my E2 slid right down into range. I was surprised, but pleased.

Click to expand...

That's good to know, did it affect your testosterone panel in any other ways.

Vince said:

That's good to know, did it affect your testosterone panel in any other ways.

Click to expand...

Free testosterone remained where it has been since first levels were stabilized. Total testosterone did increase, but not to the point of significance. SHBG was stable.

fmalianos said:

Yeah but I like to split my doses into 3 times a week. At one point I was doing daily, then went to EOD and now 3x per week. If there's a benefit to going back to daily (night time) I might try that out . Thanks for your input 

Click to expand...

How do you feel on 3 times per week? How did you feel on every day inject? What caused you to switch? I guess im lucky in that I have done inject every 3.5 days with no problems and feel great. I think I would have needle fatigue if I had to inject every day or every other.

Lancealot said:

How do you feel on 3 times per week? How did you feel on every day inject? What caused you to switch? I guess im lucky in that I have done inject every 3.5 days with no problems and feel great. I think I would have needle fatigue if I had to inject every day or every other.

Click to expand...

Oddly, I don't have any issues with daily injection. I expected to, fully expected to, but it's a part of my morning routine. But, you're right, had every 3.5 days worked, I'd have been delighted. All in the effort, successful, to manage E2 without an AI.

I can understand why one would inject every day to have more control over E to avoid an AI. That's great that you got it figured out CoastWatcher. Seems like its highly individual as far as protocols go and what works for each of us. I guess I was curious if he was having trouble with E or something else that caused him to switch to more frequent injections.